NYU Dataset
Lymphatic Vessel Transit Seeds Precursors to Cytotoxic Resident Memory T Cells in Skin Draining Lymph Nodes
Part of: Lund Lab |
UID: 10653
- Description
Resident memory T cells (TRM) provide localized protection in peripheral tissues to pathogens and cancer. However, how they develop during primary infection and their functional significance still remains unclear. This study observed the anatomical distribution of anti-viral CD8+ T cells as they simultaneously seed skin and lymph nodes (LN) TRM. They used a model of skin infection with restricted antigen distribution. The dataset contains single cell RNA sequencing data. These data reveal that contraction of peripheral tissue anti-viral responses coincides with seeding of TRM in the LN.
CD90.1 mice
Nur77-GFP mice
P14 TCR-Tg mice
C57BL/6J mice
OT-1 mice
Kaede-Tg mice
K14-VEGFR3-Ig mice
Associated Publications
Data Type
Equipment Used
Software Used
Access
- Restrictions
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Application RequiredAuthor Approval Required
- Instructions
- Please complete the Data Request Form to request access to this dataset. The information included in the form will be sent to the Corresponding Author who will evaluate your request for their data. The Corresponding Author may ask you to provide additional information if necessary.
Leica Cryostat
- Grant Support
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Lloyd J. Old STAR Program/Cancer Research InstituteRSG-18-169-01-LIB/American Cancer SocietyAACR-BMS Midcareer Female Investigator Grant/American Association for Cancer Research
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