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Results Found: 83
  • Framingham Heart Study

    Alternate Title(s)
    FHS
    Authors
    Vasan S. Ramachandran
    Emelia J. Benjamin
    L. Adrienne Cupples
    R. Curtis Ellison
    7 more author(s)...
    Description

    The Framingham Heart Study (FHS) is an ongoing cohort study dedicated to identifying common factors or characteristics that contribute to cardiovascular disease (CVD). It is a collaborative project of the National Heart, Lung and Blood Institute and Boston University. In 1948, an original cohort of 5,209 men and women between 30 and 62 years old were recruited from Framingham, MA. An Offspring Cohort...

    Subject
    Chronic Disease
    Genomics
    Health Status
    Population Characteristics
    Risk Factors
    Access Rights
    Fee Required
    Application Required
    Local Expert
    Jaime Ramos-Cejudo
    Niyati Parekh
  • Women's Health Initiative

    Alternate Title(s)
    WHI
    Description

    The Women's Health Initiative (WHI) is a longitudinal national health study sponsored by the National Heart, Lung, and Blood Institute (NHLBI) that focuses on strategies for preventing heart disease, breast cancer, colorectal cancer, and osteoporotic fractures in postmenopausal women in the United States. The study includes data from 161,808 women aged 50-79 years old at the time of enrollment. Available...

    Subject
    Cancer
    Chronic Disease
    Genomics
    Health Status
    Mental Health
    Risk Factors
    Access Rights
    Application Required
    Local Expert
    Jeffrey S. Berger
    Lila Nachtigall
  • Clinical Proteomic Tumor Analysis Consortium Data

    Alternate Title(s)
    CPTAC
    Description

    The Clinical Proteomic Tumor Analysis Consortium (CPTAC) analyzes cancer biospecimens by mass spectrometry, characterizing and quantifying their constituent proteins, or proteome. Proteomic analysis for each CPTAC study is carried out independently by Proteomic Characterization Centers (PCCs) using a variety of protein fractionation techniques, instrumentation, and workflows. Mass spectrometry and...

    Subject
    Cancer
    Genomics
    Proteomics
    Access Rights
    Free to All
    Local Expert
    David Fenyo
    Kelly V. Ruggles
  • NYU Dataset

    Genomic data for the testing of gold-standard networks of direct regulatory interactions in Saccharomyces cerevisiae

    Authors
    Sisi Ma
    Alexander Statnikov
    Description

    This data was created and compiled as researchers built genome-scale gold-standard networks of direct regulatory interactions in Saccharomyces cerevisiae that incorporate binding and gene knockout data. The research team used seven performance measurements to see the accuracy of eighteen statistics association-based approaches for de-novo network reverse-engineered in 13 different datasets spanning...

    Subject
    Genomics
    Access Rights
    Free to All
  • NYU Dataset

    SARS-CoV-2 Sequences from the NYU Langone Health COVID-19 Inpatient and Outpatient Population

    Authors
    Matthew T. Maurano
    Sitharam Ramaswami
    Paul Zappile
    Dacia Dimartino
    41 more author(s)...
    Description

    The dataset includes 864 genomic sequences obtained from COVID-19 patients aged 18 years old and above within the NYU Langone Health system between March 12 and May 10, 2020. Patients reflected the health system's catchment area (i.e., the greater New York City metropolitan area). rRNA-depleted total RNA was sequenced, underwent quality control, and analyzed to produce phylogenetic trees. Further...

    Subject
    COVID-19
    Genomics
    Infectious Disease
    Risk Factors
    Timeframe
    2020
    Access Rights
    Free to All
    Application Required
  • All of Us Research Hub

    Description

    With an emphasis on reaching historically underrepresented populations, the All of Us Research Program recruits adults aged 18 and above across the United States to share their health data to enable new insights into human health and research on precision medicine. Participants contribute electronic health records (EHR), survey responses, biospecimens, wearable devices (biometrics), and physical measurements....

    Subject
    COVID-19
    Electronic Health Records
    Genomics
    Health Care System
    Health Status
    Mental Health
    Population Characteristics
    Risk Factors
    Access Rights
    Application Required
    All NYU
    Local Expert
    Fred LaPolla
  • NYU Dataset

    Dataset and Code to Model Dispersal Dynamics of SARS-CoV-2 Lineages During the First Epidemic Wave in New York City

    Authors
    Simon Dellicour
    Samuel L. Hong
    Bram Vrancken
    Antoine Chaillon
    9 more author(s)...
    Description

    To construct a fixed time-scaled phylogenetic tree, the investigators combined 828 viral genome sequences obtained from COVID-19 patients at NYU Langone Health between March and May 2020 with 1,899 background sequences that were contributed to the Nextstrain repository. A total of 2,727 SARS-CoV-2 genomic sequences are available in the dataset. The supporting R code included with the dataset will produce...

    Subject
    COVID-19
    Genomics
    Infectious Disease
    Timeframe
    2020
    Access Rights
    Free to All
  • NYU Dataset

    Sequencing Data for a Delta-Omicron Recombinant in an Immunosuppressed Transplant Recipient Treated with Monoclonal Antibody Sotrovimab

    Authors
    Ralf Duerr
    Hao Zhou
    Takuya Tada
    Dacia Dimartino
    18 more author(s)...
    Description

    A Delta-Omicron recombinant of the SARS-CoV-2 virus was sequenced and isolated from an immunosuppressed and unvaccinated male kidney transplant patient who received Sotrovimab for treatment of COVID-19. Further clinical details and medical history of the patient are described in the associated publication. Sotrovimab is a therapeutic monoclonal antibody (mAb) used to treat infections by the BA.1 Omicron...

    Subject
    COVID-19
    Genomics
    Infectious Disease
    Timeframe
    2022
    Access Rights
    Free to All
    Application Required
  • NYU Dataset

    ORF2p Eludes Detection in Mass Spectrometry-Based Tumor Proteome Profiling

    Authors
    Daniel Ardeljan
    Xuya Wang
    Mehrnoosh Oghbaie
    Martin S. Taylor
    15 more author(s)...
    Description

    This study showed that long interspersed element-1 (LINE-1) ORF2p expression is almost undetectable in human cancers. LINE-1 is the major driver of mobile DNA activity in humans. When expressed, LINE-1 loci produce bicistronic transcripts encoding two proteins essential for retrotransposition, ORF1p and ORF2p. ORF2p expression is not well characterized in human tissues and cell lines. For the study,...

    Subject
    Genomics
    Proteomics
    Access Rights
    Free to All
  • NYU Dataset

    RNA and TCR Sequencing Characterized Cytotoxic T Cells and TCR Clonality in Organ Transplant Recipients with Squamous Cell Carcinoma

    Authors
    Nicholas Frazzette
    Alireza Khodadadi-Jamayran
    Nicole Doudican
    Alexis Santana
    4 more author(s)...
    Description

    This dataset was collected to show that there is a decline in cytotoxic T cells and TCR clonality in organ transplant recipients (OTRs) with squamous cell carcinoma (SCC). In this study, 5 SCC tumor samples and 6 transplant-associated SCC (TSCC) tumor samples were analyzed. Among SCC samples, the male to female ratio was 3 to 2 and the mean patient age was 81 years. Among TSCC samples, the male to...

    Subject
    Cancer
    Genomics
    Surgery
    Access Rights
    Free to All