With an emphasis on reaching historically underrepresented populations, the All of Us Research Program recruits adults aged 18 and above across the United States to share their health data to enable new insights into human health and research on precision medicine. Participants contribute electronic health records (EHR), survey responses, biospecimens, wearable devices (biometrics), and physical measurements.

The six All of Us surveys assess the areas listed below:

• Basic demographic information
• Lifestyle/substance use (i.e., tobacco, alcohol, and recreational drugs)
• Overall health (general health status, daily activities, and women’s health)
• Medical history (medical conditions and approximate age of diagnosis)
• Family medical history (medical history of immediate biological family members)
• Health care access and utilization (self-reported use of various health services)

There are currently three tiers of data access.

• Public Tier: Anonymized, aggregate data that can be viewed with the Data Browser.
• Registered Tier: Contains individual-level data and is available only to approved researchers on the Researcher Workbench. Authorized users also have access to tools such as the Cohort Builder, Jupyter Notebooks, and Dataset Builder.
• Controlled Tier: Includes genomic data in the form of whole genome sequencing and genotyping arrays, demographic data fields from EHRs and surveys that are suppressed in other tiers, and unshifted dates.