The Framingham Heart Study (FHS) is an ongoing cohort study dedicated to identifying common factors or characteristics that contribute to cardiovascular disease (CVD). It is a collaborative project of the National Heart, Lung and Blood Institute and Boston University.

In 1948, an original cohort of 5,209 men and women between 30 and 62 years old were recruited from Framingham, MA. An Offspring Cohort began in 1971, an Omni Cohort in 1994, a Third Generation Cohort in 2002, a New Offspring Spouse Cohort in 2004 and a Second Generation Omni Cohort in 2003. Core research in the dataset focuses on cardiovascular and cerebrovascular diseases. The data include biological specimens, molecular genetic data, phenotype data, samples, images, participant vascular functioning data, physiological data, demographic data, and ECG data.

1948 - Present
Geographic Coverage
Massachusetts - Framingham
Local Expert
Subject of Study
Subject Domain
Population Age
Adult (19 years - 64 years)
Senior (65 years - 79 years)
Aged (80 years and over)


Fee Required
Application Required

For data that cannot be obtained through the NIH BioLINCC and dbGaP repositories, researchers must submit an application for access to the internal repository.

Research beyond the core aspects of the FHS mission can be initiated as ancillary studies and the study encourages collaboration with FHS investigators, though it is not required.

Access via FHS

Research Application

Access via dbGaP

Genotype and phenotype data
Accession #: phs000007.v33.p14

Access via BioLINCC

Epidemiologic data

Access via BioLINCC

Epidemiologic data (3rd generation cohort)

Access via BioLINCC

Original FHS cohort data

Access via BioLINCC

FHS offspring epidemiology data

Associated Publications
Data Type
Dataset Format(s)
PubMed Search
View articles which use this dataset
Other Resources