This dataset is composed of eight bilateral silicon-probe multi-cellular electrophysiological recordings performed on four male Long-Evans rats. These recordings were performed to assess the effect of novel spatial learning on hippocampal CA1 neural firing and LFP patterns in naïve animals. Each session consisted of a long (~4 hour) PRE rest/sleep epoch home-cage recordings performed in a familiar...

The data set contains recordings made from multiple anterior thalamic nuclei, mainly the antero-dorsal (AD) nucleus, and subicular areas, mainly the post-subiculum (PoS), in freely moving mice. Thalamic and subicular electrodes yielding high number of the so-called Head-Direction (HD) cells were likely to be located in the AD nucleus and the PoS, respectively. Electrode placement was confirmed by histology....

The data set contains multichannel simultaneous recordings made from layer CA1 of the right dorsal hippocampus of three Long-Evans rats during open field tasks in which the animals chased randomly placed drops of water or pieces of Froot Loops while on an elevated square platform. In order to examine the temporal relationships between theta oscillations and the coordination of neuronal firing in the...

This dataset of multi single neuron recordings was acquired from three rats (EE, FF, GG) while they performed a working memory task. Neuronal activity was monitored simultaneously in the PFC (64 channels) and the intermediate CA1 (32 channels) of the hippocampus. In one rat (EE), sleep was also recorded before and after the task. The data was obtained during 52 main recording sessions and nine short...

This data contains recordings from the rat frontal cortex (brain regions mPFC, OFC, ACC, and M2) during wake-sleep episodes where at least 7 minutes of wakefulness are followed by 20 minutes of sleep. The data was recorded using silicon probe electrodes in the frontal cortices of male Long Evans rats between 4-7 months of age during no specific behavior, task or stimulus. The animal was left alone...

This data collection includes neural recordings obtained from the visual cortex (V1 and V2) and prearcurate gyrus (8Ar) of macaque monkeys (Macaca nemestrina and Macaca mulatta) during a direction discrimination task and code for replicating the modeling of neural representations. 96-channel microelectrode Utah arrays were implanted across the border of the V1 and V2 visual cortices of Macaca nemestrina....

This dataset includes 3D scanning electron microscopy (SEM) images of a female mouse corpus callosum and MATLAB code for random walker (RaW) segmentations of myelinated axons. The code additionally characterizes inner axonal diameters and fiber orientation dispersion within segments of the intra-axonal spaces and myelin sheaths. In the study, a female 8-week-old C57BL/6 mouse was perfused trans-cardiacally...

The dataset contains data collected from twelve Balb/c mice with metastatic breast cancer (4T1 mammary tumors). Six mice were in the control group and six mice were treated with 5-Fluorouracil (5FU) for metronomic chemotherapy for two weeks. Diffusion MRI (dMRI) and Dynamic Contrast-enhanced MRI (DCE-MRI) images were collected at baseline and post-treatment. Immunohistochemically (IHC) stains and measurements...

The investigators collected behavioral data from two macaque monkeys (M1 and M2) who were presented with a direction discrimination task with post-decision wagering. These monkeys received prior training to report the net direction of motion of a set of randomly moving dots. In each trial, the subject fixed their gaze on an initial fixation point, then red dots would appear on the periphery of the...

Using a Y-shaped maze, several experiments were developed to assess conditions of associative learning among fruit fly larvae. Prior to the start of the experiments, some fruit fly larvae were fed a diet of all-trans-retinal (ATR), which is a co-factor for csChrimson activation (eliciting escape behavior in flies which perceive red light). A subgroup of larvae who were fed ATR also received cycloheximide...