NYU Dataset
Translational Regulation of TFH Cell Differentiation and Autoimmune Pathogenesis
Part of: Schneider Lab |
UID: 10643
- Description
T follicular helper (TFH) cells are CD4+ T helper cells that are important for immune responses to infection and vaccination. This study examined the translational regulation required for CD4+ T helper cells to differentiate to TFH cells and its contribution to TFH cell participation in pathogenesis in autoimmune disease in animal models. The experiments for non-autoimmune studies were performed with 5 to 10 mice per group, while the experiments for autoimmune studies were performed with 10 to 20 mice per group. This dataset contains RNA sequencing data as well as supplementary data tied to the publication. The supplementary data includes raw and analyzed RNA sequencing data, list of mRNAs, viability dye, antibody clones, and dilutions.
CD45.1 mice
C57BL/6 CD45.2 mice
OT2 mice
2D2 mice
IL-21 vivid VFP mice
Associated Publications
Data Type
Equipment Used
Software Used
Access
- Restrictions
-
Free to All
- Instructions
- Raw RNA sequencing data developed in this study are available from Gene Expression Omnibus (GEO). All other data are present in the paper on PubMed Central (PMC) under Supplementary Materials.
- Grant Support
-
Jan Vilcek/David Goldfarb Fellowship/NYU Langone HealthJudith & Stewart Colton Center for Autoimmunity/NYU Langone HealthBernard Levine Postdoctoral Fellowship in Immunology/NYU Grossman School of MedicineLLS Scholar Award/Leukemia & Lymphoma Society
Do you have or know of a dataset that should be added to the catalog? Let us know!