NYU Dataset
Adipose Tissue Macrophages Adapt to Inflammatory and Metabolic Challenges
UID: 10615
- Description
Adipose tissue macrophages (ATMs) change during metabolic stress and are thought to contribute to metabolic syndrome. This study examined ATM subpopulations in steady state and in response to nutritional and infectious challenges. They characterized the epididymal white adipose tissue (eWAT) lymphoid and myeloid cell populations under steady state using RNA sequencing to analyze the transcriptome of purified eWAT monocytes, macrophages, and dendritic cells. This dataset includes RNA sequencing data. The data indicate that ATM populations dynamically adapt to metabolic stress and inflammation, which suggests that there is an important role for these cells in maintaining tissue homeostasis.
Staphylococcus aureus
SL1344
C57BL/6J mice
Cx3cr1-GFP mice
Foxp3GFP mice
Cx3cr1CRE-ERT2-YFP × Rosa26LSL-DsRed mice
CD45.1 mice
Associated Publications
Data Type
Equipment Used
Software Used
Access
- Restrictions
-
Free to All
- Instructions
- RNA sequencing data are deposited at the Gene Expression Omnibus (GEO) repository.
OneTouch Glucose Meter
Inspector Pro
- Grant Support
-
CNPq Fellowship/National Council for Scientific and Technological DevelopmentCAPES Postdoctoral Fellowship/Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior
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