NYU Data Catalog

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  • NYU Dataset

    Spatial Transcriptomics Stratifies Psoriatic Disease Severity

    Authors
    Rochelle L. Castillo
    Ikjot Sidhu
    Igor Dolgalev
    Tinyi Chu
    21 more author(s)...
    Description

    This study described human psoriasis (PsO), which is a prototypic immune-mediated condition with a high predilection for extra-cutaneous involvement. Although the cellular and molecular features of human inflammatory skin diseases have been identified, their tissue context and systemic impact remains unclear. Spatial transcriptomics was performed to explain the cellular landscape of both healthy and...

    Subject
    Genomics
    Access Rights
    Free to All
  • NYU Dataset

    Adipose Tissue Macrophages Adapt to Inflammatory and Metabolic Challenges

    Authors
    Hernandez Moura Silva
    Andre Bafica
    Gabriela Flavia Rodrigues-Luiz
    Jingyi Chi
    13 more author(s)...
    Description

    Adipose tissue macrophages (ATMs) change during metabolic stress and are thought to contribute to metabolic syndrome. This study examined ATM subpopulations in steady state and in response to nutritional and infectious challenges. They characterized the epididymal white adipose tissue (eWAT) lymphoid and myeloid cell populations under steady state using RNA sequencing to analyze the transcriptome of...

    Subject
    Genomics
    Access Rights
    Free to All
  • NYU Dataset

    SARS-CoV-2 infection triggers pro-atherogenic inflammatory responses in human coronary vessels

    Authors
    Natalia Eberhardt
    Maria G. Noval
    Ravneet Kaur
    Letizia Amadori
    19 more author(s)...
    Description

    This study combined multiple techniques (e.g., RNAscope in-situ hybridization, immunohistochemistry, immunofluorescence, single-cell RNA sequencing, bulk RNA sequencing, and functional assays) to investigate the inflammatory response associated with SARS-CoV-2 infection in human vascular tissues. Single cell RNA-sequencing data obtained from samples collected for this study is available via the Gene...

    Subject
    COVID-19
    Infectious Disease
    Risk Factors
    Access Rights
    Free to All