NYU Dataset
Neural Cell Adhesion Molecule Required for Ventricular Conduction System Development
UID: 10649
- Description
The Purkinje cells (PCs) within the ventricular conduction system (VCS) has been widely investigated, because they are necessary for synchronous activation of the ventricular myocardium. This study identified genes that might influence PC development and VCS function. The differential transcriptional profiling revealed several highly enriched cell adhesion molecules in PCs. They uncovered two additional highly enriched immunoglobulin superfamily of cell adhesion molecules (IgSF-CAMs) in the VCS: activated leukocyte cell adhesion molecule (Alcam) and neural cell adhesion molecule 1 (Ncam-1). This dataset includes RNA sequencing data. The data provide insights into the complex developmental biology of the VCS.
Alcam−/− mice
C57BL/6 mice
Cntn2-EGFP mice
Cntn2−/− mice
Associated Publications
Data Type
Equipment Used
Software Used
Access
- Restrictions
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Free to All
- Instructions
- RNA sequencing data have been deposited in Gene Expression Omnibus (GEO).
- Grant Support
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