NYU Data Catalog

NYU Dataset

Authors: Mindong Ren

Yang Xu

Colin K. L. Phoon

Hediye Erdjument-Bromage

4 more author(s)...
Description: This study used proteomic analysis, respirometry, and electron microscopy to examine the development of condensed mitochondria. The dataset contains proteomic and imaging data. The data indicate that condensed mitochondria formed from orthodox mitochondria during meiosis in order to support the formation of the acrosomal matrix. Condensed mitochondria also respired more actively and contained more...
Subject: Proteomics
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NYU Dataset

Authors: Xuhui Zheng

Gerben Marsman

Keenan A. Lacey

Jessica R. Chapman

3 more author(s)...
Description: Leukocidins are crucial components of Staphylococcus aureus (S. aureus) and they are secreted toxins that directly target and lyse immune cells. One of the leukocidins, Leukocidin AB (LukAB), is associated with the bacterial cell envelope. This study examined how S. aureus regulates LukAB secretion as well as the role of bacteria-associated LukAB in host-pathogen interaction. They used tissue culture...
Subject: Cell Physiology

Proteomics
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NYU Dataset

Authors: Chantal J. M. van Opbergen

Joseph Sall

Christopher Petzold

Kristen Dancel-Manning

2 more author(s)...
Description: Previous studies showed an abundance of functional Connexin43 (Cx43) hemichannels consequent to loss of plakophilin-2 (PKP2) expression in adult murine hearts. This study combined pre-embedding immunolabeling with serial block-face scanning electron microscopy (SBF-SEM) to visualize and examine the gap junction plaque morphology. They used a murine model of cardiomyocyte-specific Tamoxifen (TAM) activated...
Subject: Cell Physiology
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NYU Dataset

Authors: Huai-Wei Huang

Hyung Don Ryoo
Description: Rhodopsins are light-detecting proteins associated with retinal chromophores. Dysfunctional Rhodopsins cause retinal degeneration in humans and model organisms. However, the mechanisms by which photoreceptors regulate Rhodopsin homeostasis remains unknown. This study performed a photoreceptor-specific gene expression profiling analysis to examine how photoreceptors respond to stress. For their investigation,...
Subject: Genomics
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NYU Dataset

Authors: Camila Delgado

Lei Bu

Jie Zhang

Fang-Yu Liu

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Description: The Purkinje cells (PCs) within the ventricular conduction system (VCS) has been widely investigated, because they are necessary for synchronous activation of the ventricular myocardium. This study identified genes that might influence PC development and VCS function. The differential transcriptional profiling revealed several highly enriched cell adhesion molecules in PCs. They uncovered two additional...
Subject: Genomics
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NYU Dataset

Authors: Ray Chang

Ari Davydov

Pattana Jaroenlak

Breane Budaitis

3 more author(s)...
Description: Microsporidia are obligate intracellular parasites that use an unusual invasion organelle called the polar tube (PT), which is ejected from a dormant spore at ultra-fast speeds, to infect host cells. This study used serial block-face scanning electron microscopy (SBF-SEM) to capture 3-dimensional snapshots of Anncaliia algerae spores in different states of the PT ejection process. They proposed a theoretical...
Subject: Infectious Disease
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