NYU Dataset
Drosophila Fatty Acid Binding Protein Essential for Light-Dependent Rhodopsin-1 Degradation and Photoreceptor Survival
Part of: Ryoo Lab |
UID: 10641
- Description
Rhodopsins are light-detecting proteins associated with retinal chromophores. Dysfunctional Rhodopsins cause retinal degeneration in humans and model organisms. However, the mechanisms by which photoreceptors regulate Rhodopsin homeostasis remains unknown. This study performed a photoreceptor-specific gene expression profiling analysis to examine how photoreceptors respond to stress. For their investigation, they used Drosophila as a model since it has multiple Rhodopsins. The dataset contains RNA sequencing data. These data revealed that Drosophila fatty acid binding protein is a gene required for Rhodopsin-1 protein homeostasis and photoreceptor survival.
Access
- Restrictions
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Free to All
- Instructions
- RNA sequencing raw data have been deposited in Gene Expression Omnibus (GEO). All other relevant data are available on PubMed Central (PMC) under Supplementary Materials.
Real Time Analysis v3.4.4
- Grant Support
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