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Results Found: 9
  • NYU Dataset

    Human Oral Microbiota Composition Data from UAE Healthy Future Study (UAEHFS) Pilot Participants

    Authors
    Yvonne Vallès
    Claire K. Inman
    Brandilyn A. Peters
    Raghib Ali
    24 more author(s)...
    Description

    This dataset includes 330 Emirati adults participating in the UAE Healthy Future Study-Pilot (UAEHFS-pilot) who provided mouthwash samples. There were 225 non-smokers and 105 smokers who used cigarettes, dokha, shisha, or a combination of tobacco products. 101 of the 105 smokers were male. Tobacco use and frequency were assessed with a structured questionnaire and urine cotinine lab results. Gene...

    Subject
    Health Status
    Risk Factors
    Access Rights
    Free to All
    Application Required
  • NYU Dataset

    Staphylococcus Aureus Cell Envelope Selectively Controls the Sorting of Selective Exoproteins

    Authors
    Xuhui Zheng
    Gerben Marsman
    Keenan A. Lacey
    Jessica R. Chapman
    3 more author(s)...
    Description

    Leukocidins are crucial components of Staphylococcus aureus (S. aureus) and they are secreted toxins that directly target and lyse immune cells. One of the leukocidins, Leukocidin AB (LukAB), is associated with the bacterial cell envelope. This study examined how S. aureus regulates LukAB secretion as well as the role of bacteria-associated LukAB in host-pathogen interaction. They used tissue culture...

    Subject
    Cell Physiology
    Proteomics
    Access Rights
    Free to All
  • NYU Dataset

    The Effects of Whole Grains Versus Refined Grains Diets on the Microbiome in Pregnancy

    Authors
    Haipeng Sun
    Pamella Yamada
    Alexandra Paetow
    Michael Chan
    4 more author(s)...
    Description

    Between August 2017 and April 2019, 303 women in their first or second gestational trimester were enrolled in an interventional randomized controlled trial to investigate the outcomes associated with dietary plans with different proportions of total carbohydrates. Eligible women were aged 18 to 45 years old who did not have a high risk pregnancy, chronic renal disease, cancer, congestive heart failure,...

    Subject
    Pregnancy
    Risk Factors
    Access Rights
    Free to All
  • NYU Dataset

    Gut microbiome dysbiosis in antibiotic-treated COVID-19 patients is associated with microbial translocation and bacteremia

    Authors
    Lucie Bernard-Raichon
    Mericien Venzon
    Jon Klein
    Jordan E. Axelrad
    21 more author(s)...
    Description

    To investigate the relationship between gut microbiome dysbiosis and translocation of bacteria into the blood during SARS-CoV-2 infection in humans, researchers obtained blood culture and stool samples from positive COVID-19 patients who were seen at NYU Langone Health and Yale New Haven Hospital. 67 stool samples were obtained from 60 patients at NYU Langone Health and 63 samples were obtained from...

    Subject
    COVID-19
    Genomics
    Infectious Disease
    Risk Factors
    Timeframe
    2020
    Access Rights
    Free to All
  • NYU Dataset

    Isolation of Clostridia from the Gut Microbiome of Helminth-Colonized Humans

    Authors
    Shushan Sargsian
    Ze Chen
    Soo Ching Lee
    Amicha Robertson
    14 more author(s)...
    Description

    Helminth colonization has been associated with altered composition of the gut microbiota, such as increases in Clostridia. However, it is unclear if specific bacterial species display differential effects on helminth reproduction. This study isolated and sequenced the genome of 13 Clostridia from the Orang Asli, an indigenous population in Malaysia with a high prevalence of helminth infections. Metagenomic...

    Subject
    Genomics
    Access Rights
    Free to All
  • NYU Dataset

    Transcription Factor RORα Enforces Stability of the Th17 Cell Effector Program

    Authors
    Jason A. Hall
    Maria Pokrovskii
    Lina Kroehling
    Bo-Ram Kim
    4 more author(s)...
    Description

    The transcription factor RORγt is important for T helper 17 (Th17) cell differentiation. This study examined the role of the closely-related RORα in regulating the Th17 effector program. For the study, mouse T cells were purified from lymph nodes and spleens of six to eight week old mice. The dataset includes RNA sequencing analysis of ex vivo Th17 cells from draining lymph nodes or spinal cords of...

    Subject
    Genomics
    Access Rights
    Free to All
  • NYU Dataset

    COVID-19 and Infant Gut Microbiome

    Authors
    Francesca R. Querdasi
    Sarah C. Vogel
    Moriah E. Thomason
    Bridget L. Callaghan
    1 more author(s)...
    Description

    This dataset was collected for a study which examined differences in the gut microbiome within a cohort of 12-month old infants who provided samples either before the start of the COVID-19 pandemic or during the first 9 months of the pandemic. The study also assessed the demographics and health of the infants' primary caregivers, including factors such as race, ethnicity, socioeconomic status, mental...

    Subject
    COVID-19
    Mental Health
    Risk Factors
    Access Rights
    Free to All
  • NYU Dataset

    Energy Coupling and Stoichiometry of Zn2+/H+ Antiport by YiiP

    Authors
    Adel Hussein
    Shujie Fan
    Maria Lopez-Redondo
    Ian Kenney
    3 more author(s)...
    Description

    Previous studies of YiiP, bacterial Zn2+/H+ antiporter, have shown a homodimeric architecture and the presence of three distinct Zn2+ binding sites. YiiP is a representative of the cation diffusion facilitator superfamily, which are responsible for homeostasis of transition metal ions. This study used cryo-electron microscopy, microscale thermophoresis, and molecular dynamics simulations to address...

    Subject
    Cell Physiology
    Access Rights
    Free to All
  • NYU Dataset

    Food and Microbiome Longitudinal Investigation

    Alternate Title(s)
    FAMiLI, NYU Human Microbiome Study Cohort
    Authors
    Jiyoung Ahn
    Stella Yi
    Description

    Food and Microbiome Longitudinal Investigation (FAMiLI) is an ongoing prospective cohort study that has enrolled a diverse cohort in the United States to study how the human microbiome and diet are related to various chronic diseases, including cancer, heart disease, and diabetes. Eligible participants are at least 40 years old, not pregnant, and not using long-term antibiotics. As of January 2023,...

    Subject
    Chronic Disease
    Population Characteristics
    Risk Factors
    Access Rights
    Free to All