This dataset was generated by a randomized controlled trial to evaluate the effectiveness of a culturally tailored, evidence-based adherence intervention (AI) for Latino patients delivered by bilingual Health Coaches versus usual care (UC). 112 Latino patients with uncontrolled hypertension who were non-adherent to their anti-hypertensive medications were consented into the study. Data was collected...

This data contains information on patients with neurofibromatosis type 1 and neurofibromatosis type 2 and schwannomatosis. The neurofibromatoses (NF) are rare disorders with variation in clinical manifestations, and the NF Registry was created to assist researchers in studying the disease. Patients are included in the registry if they meet the diagnostic criteria for one of the three NF conditions....

Researchers imaging data along with image-processing algorithms in order to develop a set of candidate image features that can be used to develop a quantitative description of xenografted colorectal chronic tumor hypoxia. These features were used to develop a spatiotemporal logical expression as well as a way to formulate a linear regression function that uses all of the image features to describe...

This dataset was created as part of a prospective review of somatosensory evoked potential (SEP) recordings obtained during intraoperative monitoring (IOM) on instrumented spinal surgeries that were performed for chronic underlying neurologic and neuromuscular conditions, including scoliosis, myelopathy, and spinal stenosis, on patients who did not exhibit any postoperative neurologic deficits. For...

This dataset was compiled as part of an exploratory study to determine the longitudinal changes in multiple sclerosis (MS) lesions over time on ultra-high field MR imaging. Nine patients with MS underwent high-resolution 3D-susceptibility weighted imaging (SWI) and 2D-gradient-echo-T2*-weighted imaging on 7T MRI at baseline and after approximately 2.4 years for follow-up imaging. The data includes...

This dataset was collected during a prospective phase 2 double-blind randomized placebo-controlled a dose-finding clinical trial to compare the effects of three ascending doses of pyridostigmine (15, 30, and 60 mg three times daily) vs. matching placebo on post-exercise heart rate recovery and other measures of sympathovagal balance. The study included four stages: Screening, randomization, and baseline...

This dataset was generated through a prospective randomized, double-blind study to determine the effects of serial phlebotomy on vascular endothelial function in the brachial artery. Subjects of the study were 84 iron-replete, non-anemia men and post-menopausal women age 40-70 years. Subjects were randomly assigned to three study treatment groups: Four serial phlebotomy procedures each followed by...

The NYU Alzheimer’s Disease Research Center (NYU ADRC) maintains a large database of standardized clinical and neuropathological research data collected at NYU Langone Health for local investigators, as well as those at affiliated or collaborating institutions. The NYU ADRC database includes a cumulative record of over 1,500 subjects enrolled since 1972. Data was collected every two years until 2005...

The Scientific Registry of Transplant Recipients (SRTR) database includes data collected by the Organ Procurement and Transplantation Network (OPTN), supplemented with data from the Centers for Medicare & Medicaid Services (CMS) and the National Technical Information Services (NTIS) Death Master File. The database allows organ transplant programs to register candidates for transplant, match donated...

This dataset was collected as part of a double-blind, placebo-controlled, randomized clinical trial to determine the effects of intravenous rHuEpo (200U/kg daily for three consecutive days) on measures of platelet and endothelial cell activation, soluble Fas ligand, and peripheral blood mononuclear cell (PBMC) expression of angiogenesis signaling proteins. The study included 44 adults over 21 years...