NYU Dataset
Early-Life Antibiotic Exposure Alters Intestinal Microbiome Composition
UID: 10627
- Description
Early-life antibiotic exposures during postnatal development have lasting effects on microbiota composition. Previous studies in humans and mice have found altered microbial composition to be associated with enhanced disease susceptibility and modified immune status. They investigated impact of timing of antibiotic exposure by treating 5 to 9 days C57BL/6J mice with two of the most commonly prescribed medications, amoxicillin or azithromycin, in children. The dataset contains 16S rRNA sequencing data. This study showed that constituents of the early-life microbiota composition are critical to intestinal immune maturation.
MG1655
HMXZ001
Associated Publications
Data Type
Equipment Used
Software Used
Access
- Restrictions
-
Free to All
- Instructions
- 16S rRNA sequencing data are available in Qiita. Qiita is an entirely open-source microbial study management platform. Users need to create an account with Qiita to access any studies and files available.
Qubit Fluorometer
- Grant Support
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Sergei S. Zlinkoff Fund/Sergei S. Zlinkoff FundTransatlantic Network of Excellence/Leducq FondationEmch Foundation/Emch FoundationBernard Levine Postdoctoral Fellowship in Immunology/NYU Langone HealthBSCGIO 462 157841/1/Swiss National Science Foundation
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