NYU Data Catalog

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  • Myeloma XI: Paired Presentation, Relapse and Control Samples From Newly Diagnosed, Uniformly Treated Myeloma Patients

    Authors
    Graham Jackson
    Description

    Randomised Comparisons, in Myeloma Patients of All Ages, of Thalidomide, Lenalidomide, Carfilzomib and Bortezomib Induction Combinations, and of Lenalidomide and Combination Lenalidomide Vorinostat as Maintenance (Myeloma XI) was a randomized controlled trial which recruited 4420 adult patients in the United Kingdom who were newly diagnosed with symptomatic or non-secretory multiple myeloma to study...

    Subject
    Cancer
    Genomics
    Risk Factors
    Access Rights
    Application Required
    Author Approval Required
    Local Expert
    Gareth J. Morgan
  • NYU Dataset

    NYU Women's Health Study: Temporal Reproducibility of IgG and IgM Autoantibodies in Serum from Healthy Women

    Alternate Title(s)
    NYUWHS
    Authors
    Tess Clendenen
    Shaohui Hu
    Yelena Afanasyeva
    Manor Askenazi
    7 more author(s)...
    Description

    Study investigators examined blood samples from participants in the NYU Women’s Health Study (NYUWHS)--a cohort of 14,274 women enrolled between 1985 and 1991 through a breast cancer screening center in New York City--to identify autoantibodies associated with healthy women. The blood samples were collected at the time of enrollment and at annual screening visits until 1991 and long term follow-up...

    Access Rights
    Free to All

  • Bone marrow microenvironments that contribute to patient outcomes in newly diagnosed multiple myeloma

    Authors
    Samuel A. Danziger
    Mark McConnell
    Jake Gockley
    Mary H. Young
    29 more author(s)...
    Description

    This dataset contains data on the tumor microenvironment from the whole bone marrow of 436 patients who were diagnosed with multiple myeloma and enrolled in the interventional Total Therapy trial series conducted by the University of Arkansas for Medical Sciences. 266 male and 170 female patients were enrolled between February 25, 2004 and January 11, 2014 and completed 25 to 5,241 days of follow-up...

    Subject
    Cancer
    Chronic Disease
    Genomics
    Access Rights
    Free to All
    Local Expert
    Gareth J. Morgan
  • NYU Dataset

    Early-Life Antibiotic Exposure Alters Intestinal Microbiome Composition

    Authors
    Timothy C. Borbet
    Miranda B. Pawline
    Jackie Li
    Melody L. Ho
    11 more author(s)...
    Description

    Early-life antibiotic exposures during postnatal development have lasting effects on microbiota composition. Previous studies in humans and mice have found altered microbial composition to be associated with enhanced disease susceptibility and modified immune status. They investigated impact of timing of antibiotic exposure by treating 5 to 9 days C57BL/6J mice with two of the most commonly prescribed...

    Subject
    Genomics
    Access Rights
    Free to All
  • NYU Dataset

    mRNA COVID-19 vaccine elicits potent adaptive immune response without the acute inflammation of SARS-CoV-2 infection

    Authors
    Ellie Ivanova
    Jasmine Shwetar
    Joseph C. Devlin
    Terkild B. Buus
    17 more author(s)...
    Description

    To investigate immune responses to SARS-CoV-2 antigens under various inflammatory conditions, researchers collected blood samples from five adult patients seen at NYU Langone Health with lab-confirmed cases of acute COVID-19 and from nine healthy adults (seven who had received the BNT162b2 mRNA vaccine and two with no prior exposure to SARS-CoV-2). Samples were obtained at multiple time points. Patients...

    Subject
    COVID-19
    Genomics
    Infectious Disease
    Access Rights
    Free to All