NYU Data Catalog

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  • NYU Dataset

    Multi-unit spiking activity recorded from rat frontal cortex

    Alternate Title(s)
    FCX-1
    Authors
    Brendon O. Watson
    Daniel Levenstein
    J. Palmer Greene
    Jennifer N. Gelinas
    1 more author(s)...
    Description

    This data contains recordings from the rat frontal cortex (brain regions mPFC, OFC, ACC, and M2) during wake-sleep episodes where at least 7 minutes of wakefulness are followed by 20 minutes of sleep. The data was recorded using silicon probe electrodes in the frontal cortices of male Long Evans rats between 4-7 months of age during no specific behavior, task or stimulus. The animal was left alone...

    Subject
    Neuroscience
    Access Rights
    Free to All
  • NYU Dataset

    Optogenetic Activation of ID2/Nkx2.1 Interneurons in the Posterior Parietal Cortex During NREM Sleep

    Authors
    Manuel Valero
    Tim J. Viney
    Robert Machold
    Sara Mederos
    5 more author(s)...
    Description

    This study described a unique set of deep layer neurons in posterior parietal cortex (PPC) whose spiking activity is inversely correlated with all principal cells and interneurons in all brain states, but most commonly during the down state of non-REM (NREM) sleep. They identified down state-active (DSA) neurons as deep layer neocortical neurogliaform cells that express ID2 and Nkx2.1. For this study,...

    Subject
    Neuroscience
    Access Rights
    Free to All
  • NYU Dataset

    Brain-Wide Interactions During Hippocampal Sharp Wave Ripples

    Authors
    Noam Nitzan
    Rachel Swanson
    Dietmar Schmitz
    Gyorgy Buzsaki
    Description

    Many experiments have characterized the bidirectional relationship between sharp wave ripples (SPW-Rs) and activity in chosen brain areas. However, the topographic relationship between different segments of the hippocampus and brain-wide target areas has not been studied at high temporal and spatial resolution. This study analyzed two publicly available datasets with simultaneous high-density silicon...

    Subject
    Neuroscience
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    Free to All
  • NYU Dataset

    Routing of Hippocampal Ripples to Subcortical Structures via the Lateral Septum

    Authors
    David Tingley
    Gyorgy Buzsaki
    Description

    The function of hippocampal sharp-wave ripples (SPW-Rs) relate to the consolidation of recent experiences and planning of future actions. This study investigated the impact of SPW-Rs on the firing patterns of lateral septal (LS) neurons in behaving rats. The experiments were performed on Long-Evans rats. For this study, they examined the hippocampal-LS circuit by simultaneously recording activity patterns...

    Subject
    Neuroscience
    Access Rights
    Free to All
  • NYU Dataset

    Forty-Hertz Light Stimulation Does Not Entrain Native Gamma Oscillations in Alzheimer’s Disease

    Authors
    Marisol Soula
    Alejandro Martin-Avila
    Yiyao Zhang
    Annika Dhingra
    4 more author(s)...
    Description

    Alzheimer’s disease (AD) is characterized by abnormal aggregation of the proteins amyloid-β (Aβ). Recent studies showed that 40-Hz sensory stimulation is a potential treatment in AD. This study examined whether 40-Hz flickering light entrains gamma oscillations and suppresses Aβ in the brains of APP/PS1 and 5xFAD mouse models. For the study, they investigated the effect of 40-Hz light stimulation on...

    Subject
    Neuroscience
    Access Rights
    Free to All