The National Vital Statistics System (NVSS) data for the United States are provided through contracts between National Center for Health Statistics and vital registration systems operated in the various jurisdictions legally responsible for the registration of vital events (births, deaths, marriages, divorces, and fetal deaths).

The New York City Department of Health and Mental Hygiene (NYC DOHMH) has shared vital statistics data (birth and mortality data) online. Birth data includes demographic information on the mother, including age, race, and education. Mortality data includes demographic information on the deceased, such as age, sex, race, and education. The publicly-available birth and death micro-SAS datasets provide...

The Scientific Registry of Transplant Recipients (SRTR) database includes data collected by the Organ Procurement and Transplantation Network (OPTN), supplemented with data from the Centers for Medicare & Medicaid Services (CMS) and the National Technical Information Services (NTIS) Death Master File. The database allows organ transplant programs to register candidates for transplant, match donated...

The National Center for Advancing Translational Sciences (NCATS) has systematically compiled clinical, laboratory and diagnostic data from electronic health records to support COVID-19 research efforts via the National COVID Cohort Collaborative (N3C) Data Enclave. As of August 2, 2022, the repository contains information from over 15 million patients (including 5.8 million COVID-19 positive patients)...

The Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial was a large randomized controlled trial that assessed whether certain screening practices decreased deaths from prostate, lung, colorectal and ovarian cancer. Approximately 155,000 men and women aged 55 to 74 years old were enrolled from 10 screening centers across the United States between November 1993 and July 2001. Participants...

This dataset from the North American SUDEP Registry represents an ongoing collaborative effort to collect clinical information, tissue, and DNA to support research on clinical research factors for Sudden Unexpected Death in Epilepsy (SUDEP) and other causes of epilepsy-related deaths. For enrollment in the registry, at least one of the following criteria was satisfied: SUDEP within the last five...

The City Health Dashboard presents city- and/or census tract-level data for over 900 cities across the United States to describe population health within local contexts. Metrics included in the dashboard encompass five broad domains: health outcomes, social and economic factors, health behavior, physical environment, and clinical care. The underlying data originates from a combination of publicly-available...

The COVID Tracking Project provided national, state, and territory-level data on COVID-19 testing (PCR and antibody, and antigen tests), hospitalization (ever hospitalized, currently hospitalized, ventilator use, ICU admission, and total hospitalizations), and outcomes (all deaths, confirmed deaths, probable deaths, new deaths, and recoveries) within the United States and its territories. Data collection...

Through January 6, 2022, Global.health maintained an anonymized individual-level (line) dataset on COVID-19 cases. A list of all contributing institutions may be found here. The dataset collected the following information where reported/available: Demographics (e.g., sex, age range, gender, occupation, nationality, ethnicity) Geographic details Symptoms Event history (e.g., first consult...

The Colchicine Coronavirus SARS-CoV2 Trial (COLCORONA) was an international randomized double-blind controlled trial which investigated whether short-term treatment with colchicine decreased the rate of death, rate of hospitalization, and need for medical intervention among adult patients recently diagnosed with COVID-19. A secondary objective was to determine the safety of the intervention among a...