This data was collected as part of a study of Pediatric-Onset Multiple Sclerosis (POMS), and to define the neuroanatomic underpinnings of deficits identified with cognitive screening batteries in POMS. Participants with POMS (n=15) were recruited through outpatients visits at the Lourie Center for Pediatric MS at Stony Brook University Health Center, and healthy controls (n=21) were recruited through...

The NYU Alzheimer’s Disease Research Center (NYU ADRC) maintains a large database of standardized clinical and neuropathological research data collected at NYU Langone Health for local investigators, as well as those at affiliated or collaborating institutions. The NYU ADRC database includes a cumulative record of over 1,500 subjects enrolled since 1972. Data was collected every two years until 2005...

This dataset was collected for a study to replicate previous work on hippocampal physiology predictive of successful encoding using an associative memory paradigm in a surgical intracranial electroencephalography (iEEG) group and extend those investigations to a chronic ambulatory iEEG population using RNS System devices (NeuroPace, Inc.). The primary objective was to compare the hippocampal gamma...

This data was collected during clinical examinations at the NYU Comprehensive Epilepsy Center between the years of 2003 and 2008. Subjects included in this dataset have a confirmed epilepsy diagnosis from either routine electroencephalogram (EEG) or video-electroencephalogram (VEEG). The dataset does not include raw EEG data. There are 228 subjects in total. The following information was collected...

This dataset contains behavioral data assessing the sensitivity of five human subjects (one female and four male) to higher-order moments of motion as applied to random dot kinematograms. The dots were manipulated by probability distributions that systematically differed in their mean, variance, skewness, or kurtosis. Following training sessions where they reached at least 80% accuracy, subjects were...

The investigators collected simultaneous recordings using multi-channel electrode arrays attached to the prearcuate gyrus of macaque monkeys who performed a direction discrimination task with fixed stimulus duration. In the study, 96-channel multielectrode arrays were used to record from neural populations in area 8Ar of the prearcuate gyrus of three macaque monkeys, while they performed a direction...

This dataset assesses the influence of timescale on the processing of visual stimuli. Following training sessions where they reached at least 76% accuracy, five human subjects (four male and one female) were presented with the following task: brief samples of a contrast pattern were presented on screen for 200 ms, followed by a pause before the subjects were prompted to match the samples to one of...

This dataset presented results from psychophysics and modeling that supports the use of image statistics heuristics in the judgement of metallicity. To investigate visual features associated with the interpretation of metallic objects, five practiced participants (aged 23 to 28 years old) with normal color vision and normal or corrected-to-normal visual acuity were recruited to perform a conjoint-measurement...

Electrophysiological recordings were obtained from male rats who were subjected to localized cooling of their medial septum (MS) prior to completing behavioral tasks. The MS is critical in theta generation. Therefore, temperature manipulation of the MS was used to test these models. Approximately 40 control trials were completed, followed by exposure to dry ice to reduce MS temperature for 20 to 60...

Using a Y-shaped maze, several experiments were developed to assess conditions of associative learning among fruit fly larvae. Prior to the start of the experiments, some fruit fly larvae were fed a diet of all-trans-retinal (ATR), which is a co-factor for csChrimson activation (eliciting escape behavior in flies which perceive red light). A subgroup of larvae who were fed ATR also received cycloheximide...