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Results Found: 5
  • NYU Dataset

    Recordings of movement kinematics and changes of ongoing movements in human subthalamic nucleus

    Authors
    Dennis London
    Arash Fazl
    Kalman Katlowitz
    Marisol Soula
    3 more author(s)...
    Description

    39 units of electrophysiological and behavioral recordings were obtained from a total of 8 human subjects aged 46 to 66 years old with Parkinson's disease who were undergoing implantation of deep brain stimulation electrodes. The study examined neural activity in the subthalamic nucleus (STN) in a series of trials that prompted single-step and multistep reaching movements. A stereoscopic camera recorded...

    Subject
    Chronic Disease
    Neuroscience
    Access Rights
    Free to All
  • NYU Dataset

    Predicting Behavioral Dynamics in Drosophila Using Algorithms

    Authors
    Timothy A. Currier
    Katherine I. Nagel
    Description

    The algorithms used by the nervous system to integrate synergistic and conflicting stimuli across modalities are still under investigation. This study developed a closed-loop orienting paradigm in Drosophila to study the algorithms by which cues from two modalities are integrated during ongoing behavior. In the study, all experiments were performed on adult female flies three to five days after hatching....

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    Free to All
  • NYU Dataset

    Heterosynaptic Plasticity Determines the Set-Point for Cortical Excitatory-Inhibitory Balance

    Authors
    Rachel E. Field
    James A. D’amour
    Robin Tremblay
    Christoph Miehl
    3 more author(s)...
    Description

    Cortical inhibitory and excitatory inputs are initially mismatched, but become balanced with experience during development. However, how excitatory-inhibitory balance is defined at most synapses, or the mechanisms for maintaining this balance at specific set-points is still unclear. This study demonstrated how coordinated long-term plasticity calibrates populations of excitatory/inhibitory inputs onto...

    Subject
    Neuroscience
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    Application Required
    Author Approval Required
  • NYU Dataset

    Neurons Specify Goal-Directed Navigation Behaviors

    Authors
    Andrew M. M. Matheson
    Aaron J. Lanz
    Ashley M. Medina
    Al M. Licata
    3 more author(s)...
    Description

    Animals frequently combine odor cues about source identity with wind direction cues about source location to navigate towards a food source. However, where and how these two cues are integrated to support navigation remains unknown. This study described a pathway to the Drosophila fan-shaped body that encodes attractive odor and promotes upwind navigation. Behavioral experiments were performed in a...

    Subject
    Neuroscience
    Access Rights
    Free to All
  • Diagnostics, Imaging, and Genetics Network for the Objective Study and Evaluation of Chronic Traumatic Encephalopathy Research Project

    Alternate Title(s)
    DIAGNOSE CTE
    Authors
    Robert A. Stern
    Jeffrey Cummings
    Eric M. Reiman
    Martha Shenton
    Description

    Diagnostics, Imaging, and Genetics Network for the Objective Study and Evaluation of Chronic Traumatic Encephalopathy (DIAGNOSE CTE) was a longitudinal multi-site study of diagnostic methods for CTE and potential risk factors for the disease. The primary objectives of the study are to collect and analyze neuroimaging and fluid biomarkers for the detection of CTE during life, characterize its clinical...

    Subject
    Chronic Disease
    Genomics
    Mental Health
    Neuroscience
    Risk Factors
    Access Rights
    Application Required
    Author Approval Required
    Local Expert
    Hector Arciniega