Recordings of movement kinematics and changes of ongoing movements in human subthalamic nucleus
- Description
39 units of electrophysiological and behavioral recordings were obtained from a total of 8 human subjects aged 46 to 66 years old with Parkinson's disease who were undergoing implantation of deep brain stimulation electrodes. The study examined neural activity in the subthalamic nucleus (STN) in a series of trials that prompted single-step and multistep reaching movements. A stereoscopic camera recorded subjects as they controlled an on-screen cursor using free-hand movements in 3D space. In Reach trials, the subjects were cued to make a horizontal reaching movement to a target region. In Planned Turn trials, subjects were cued to make a horizontal and then upward reaching movement to a target region. In Impromptu Turn trials, subjects were initially cued to perform a horizontal movement (same as a Reach trial), however the target would change mid-movement to prompt subjects to perform a vertical movement to reach the final target.
The investigators have shared raw and processed data organized by subject folder. Each folder includes electrophysiology data, sorted spikes, and behavioral data as .mat files. Also available are time-frequency data, local field potential (LFP) data, beta-filtered analytic signal data, and pairwise phase consistency data for each subject. The processed_data.mat file contains a structure with all subjects' spiking and behavioral related data but does not contain LFP data.
Access
- Restrictions
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Free to All
- Instructions
- The data can be downloaded freely via the access link to the Dryad data repository.
- Grant Support
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Simons Collaboration on the Global Brain/542997/Simons Foundation543009/Simons Collaboration on the Global BrainMcKnight Scholar Award/McKnight FoundationPew Biomedical Scholars/Pew Charitable Trusts
- Other Resources
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Github
Cluster mass test functions