NYU Dataset

Recordings of movement kinematics and changes of ongoing movements in human subthalamic nucleus

Part of: Kiani Lab |
UID: 10458
* Corresponding Author
Description

39 units of electrophysiological and behavioral recordings were obtained from a total of 8 human subjects aged 46 to 66 years old with Parkinson's disease who were undergoing implantation of deep brain stimulation electrodes. The study examined neural activity in the subthalamic nucleus (STN) in a series of trials that prompted single-step and multistep reaching movements. A stereoscopic camera recorded subjects as they controlled an on-screen cursor using free-hand movements in 3D space. In Reach trials, the subjects were cued to make a horizontal reaching movement to a target region. In Planned Turn trials, subjects were cued to make a horizontal and then upward reaching movement to a target region. In Impromptu Turn trials, subjects were initially cued to perform a horizontal movement (same as a Reach trial), however the target would change mid-movement to prompt subjects to perform a vertical movement to reach the final target.

The investigators have shared raw and processed data organized by subject folder. Each folder includes electrophysiology data, sorted spikes, and behavioral data as .mat files. Also available are time-frequency data, local field potential (LFP) data, beta-filtered analytic signal data, and pairwise phase consistency data for each subject. The processed_data.mat file contains a structure with all subjects' spiking and behavioral related data but does not contain LFP data.

Subject of Study
Subject Domain
Population Age
Adult (19 years - 64 years)
Senior (65 years - 79 years)
Keywords

Access

Restrictions
Free to All
Instructions
The data can be downloaded freely via the access link to the Dryad data repository.
Access via Dryad

Raw electrophysiology data, sorted spikes, and behavioral data

Associated Publications
Data Type
Equipment Used
Leap Motion Controller
Software Used
Chronux
Stereotaxy
Dataset Format(s)
MATLAB
Grant Support
Simons Collaboration on the Global Brain/542997/Simons Foundation
543009/Simons Collaboration on the Global Brain
McKnight Scholar Award/McKnight Foundation
Pew Biomedical Scholars/Pew Charitable Trusts
Other Resources
Github

Cluster mass test functions