The Fragile Families and Child Wellbeing Study is following a cohort of nearly 5,000 children born in large U.S. cities between 1998 and 2000, roughly three-quarters of whom were born to unmarried parents. The study consists of interviews with both mothers and fathers at birth and again when children are ages one, three and five, plus in-home assessments of children and their home environments at ages...

The Nurses' Health Studies (NHS) are long-running, questionnaire-based studies on women's health. The study was initiated in 1976 with the NHS cohort. The initial studies focus on cancer, cardiovascular disease and risk factors for chronic health issues in women. The latest cohort, NH3, has been expanded to include both male and female registered nurses and nursing students. Survey and biospecimen...

This dataset was generated during a repeated cross-sectional national telephone survey of households, conducted as part of the evaluation of the Robert Wood Johnson Foundation's Urban Health Initiative (UHI). UHI is a long-term effort to improve the health, safety, and well-being of children and youth in five economically distressed cities in the United States: Baltimore, MD, Detroit, MI, Oakland,...

The Child Health and Development Studies (CHDS) were launched in 1959 as prospective longitudinal cohort studies on pregnancy, delivery, and child development from birth through adolescence. Between 1959 and 1967, 15,000 families with expectant mothers who were members of the Kaiser Foundation Health Plan in Oakland, California consented to enrollment. Health and lifestyle data on mothers, fathers,...

The Upstate New York Infant Development Screening (Upstate KIDS) Study is a collaboration between the New York State Department of Health, University at Albany, and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). The study includes information from over 5,034 mothers and their 6,171 children in New York State, excluding New York City, who were recruited...

Generation R is an ongoing prospective cohort study of child development from the prenatal period through young adulthood in a multi-ethnic population recruited from the Rotterdam, Netherlands metropolitan area. The study enrolled 9,778 mothers with a delivery date between April 2002 and January 2006; they had 9,749 live births. The primary objective of the study is to identify early environmental...

Baby's First Years is the first randomized controlled trial in the United States to examine the causal impact of unconditional cash payments on children's early cognitive, socio-emotional, and brain development over 52 months. Researchers recruited 1,000 mothers with infants and incomes below the federal poverty line residing near study sites in New Orleans, LA, the Twin Cities (Minneapolis, MN and...

To examine the association between fetal behavior and brain development through childhood, investigators conducted a longitudinal study with 120 normal fetuses in utero through 36 months of age recruited between 2011 and 2018 from Hutzel Women’s Hospital in Detroit, Michigan using continuous four‐dimensional functional magnetic resonance imaging (fMRI). Twelve‐minute fMRI scans were conducted in 120...

This is a single-blind, two-site randomized clinical trial which evaluated the effectiveness of the Smart Beginnings model on early school readiness in low-income families. The Smart Beginnings intervention includes a Video Interaction Project (VIP), a 14-session universal primary prevention program delivered in the pediatric clinic at the time of well-child visits from birth through 36 months, and...

This dataset was collected for a study which examined differences in the gut microbiome within a cohort of 12-month old infants who provided samples either before the start of the COVID-19 pandemic or during the first 9 months of the pandemic. The study also assessed the demographics and health of the infants' primary caregivers, including factors such as race, ethnicity, socioeconomic status, mental...