Child Health and Development Studies: Generation 1

Alternate Titles(s): CHDS
UID: 10431
Description

The Child Health and Development Studies (CHDS) were launched in 1959 as prospective longitudinal cohort studies on pregnancy, delivery, and child development from birth through adolescence. Between 1959 and 1967, 15,000 families with expectant mothers who were members of the Kaiser Foundation Health Plan in Oakland, California consented to enrollment. Health and lifestyle data on mothers, fathers, and children ('CHDS children') were collected through comprehensive interviews, Kaiser medical records, and donated biospecimens. CHDS is ongoing and is currently collecting data from a third generation of participants ('CHDS grandchildren'); this dataset record pertains to the original birth cohort, or 'Generation 1'.

Data was collected at the following timepoints:

  1. Enrollment (mother's first pregnancy contact with Kaiser)
  2. First trimester study visit
  3. Second trimester study visit
  4. Delivery (mother and infant outcomes)
  5. Child follow-up: every Kaiser visit up to 17 years
Children were also divided into subgroups to receive study examinations at the following pre-specified timepoints:
  • Two cohorts at 5 years old
  • Two cohorts at 9 to 11 years old
  • One cohort at 15 to 17 years old
Publisher
Timeframe
1959 - 1972
Geographic Coverage
California
Local Expert
Subject of Study
Subject Domain
Population Age
Child (2 years - 12 years)
Adolescent (13 years - 18 years)
Adult (19 years - 64 years)
Newborn (under 1 month)
Infant (1 month - 23 months)
Keywords

Access

Restrictions
Application Required
Instructions

A NIH account is required to access de-identified data in the Child Health and Human Development (NICHD) Data and Specimen Hub (DASH) repository. The DASH repository also contains data documentation such as the study protocol, interview questions, codebooks, and de-identification methodology.

Non-student researchers who are seeking data files that are not listed in the NICHD DASH portal must first request a CHDS Data Use Protocol through the contact form on the CHDS website.

To initiate proposals for studies that will involve contacting CHDS participants or will utilize archived blood samples, contact Dr. Barbara Cohn to request the CHDS Protocol for New Data Collections and/or CHDS Serum Archive Protocol.

Access via Data Access Application

Request biospecimens and other data not in DASH

Access via NICHDS DASH

De-identified data for Generation 1 ('Original Cohort'), protocol, and codebooks

Associated Publications
Data Type
Study Type
Observational
Dataset Format(s)
SAS, CSV
PubMed Search
View articles which use this dataset
Other Resources