NYU Dataset

In Utero Assessment of the Human Neural Connectome and Later Child Behavior

UID: 10616
Author(s): Moriah E. Thomason*
* Corresponding Author
Description

To examine the association between fetal behavior and brain development through childhood, investigators conducted a longitudinal study with 120 normal fetuses in utero through 36 months of age recruited between 2011 and 2018 from Hutzel Women’s Hospital in Detroit, Michigan using continuous four‐dimensional functional magnetic resonance imaging (fMRI). Twelve‐minute fMRI scans were conducted in 120 normal fetuses between 22 and 39 weeks gestational age. Associations between fetal brain functional connectivity, child neurobehavioral development, and maternal stress were evaluated through imaging and standardized questionnaires presented to enrolled mothers. Postnatal motor function was evaluated at 7 (n = 77) and 36 months of age (n = 89) with the motor component of the Bayley Scales of Infant Development.

Timeframe
2011 - 2022
Geographic Coverage
Michigan - Detroit
Subject of Study
Subject Domain
Population Age
Child (2 years - 12 years)
Adult (19 years - 64 years)
Infant (1 month - 23 months)
Keywords

Access

Restrictions
Free to All
Application Required
Instructions
Imaging data and clinical assessments may be requested through the National Institute of Mental Health Data Archive (NDA). Interested researchers must log in to the NDA through the Research Auth Service (RAS) with a eRA Commons account, Login.gov account, or PIV/CAC credentials, then submit a Data Access Request for this data.
Access via NDA


Accession #: 2434

Associated Publications
Data Type
Equipment Used
Siemens MAGNETOM Verio
Software Used
FSL
Mango
SPM12
TbCAPs
Study Type
Observational
Data Collection Instruments
Perceived Stress Scale (PSS)
Bayley Scales of Infant Development
Behavior Rating Inventory of Executive Function (BRIEF)
State-Trait Anxiety Inventory for Adults (STAI-AD)
Satisfaction with Life Scale
Penn State Worry Questionnaire (PSWQ)
Experience in Close Relationships Scale (ECR)
Grant Support