The Methods in Infant/Toddler Neuroimaging (MINI) study surveyed investigators at infant and toddler research laboratories across the globe to collect information on preferred practices for MRI acquisition, scan success rates, visit preparation, scanning protocols, family accommodations, study design, and addressing incidental findings. The survey was distributed in February 2021 through the Fetal,...

Generation R is an ongoing prospective cohort study of child development from the prenatal period through young adulthood in a multi-ethnic population recruited from the Rotterdam, Netherlands metropolitan area. The study enrolled 9,778 mothers with a delivery date between April 2002 and January 2006; they had 9,749 live births. The primary objective of the study is to identify early environmental...

The Upstate New York Infant Development Screening (Upstate KIDS) Study is a collaboration between the New York State Department of Health, University at Albany, and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). The study includes information from over 5,034 mothers and their 6,171 children in New York State, excluding New York City, who were recruited...

Baby's First Years is the first randomized controlled trial in the United States to examine the causal impact of unconditional cash payments on children's early cognitive, socio-emotional, and brain development over 52 months. Researchers recruited 1,000 mothers with infants and incomes below the federal poverty line residing near study sites in New Orleans, LA, the Twin Cities (Minneapolis, MN and...

To examine the association between fetal behavior and brain development through childhood, investigators conducted a longitudinal study with 120 normal fetuses in utero through 36 months of age recruited between 2011 and 2018 from Hutzel Women’s Hospital in Detroit, Michigan using continuous four‐dimensional functional magnetic resonance imaging (fMRI). Twelve‐minute fMRI scans were conducted in 120...

This is a single-blind, two-site randomized clinical trial which evaluated the effectiveness of the Smart Beginnings model on early school readiness in low-income families. The Smart Beginnings intervention includes a Video Interaction Project (VIP), a 14-session universal primary prevention program delivered in the pediatric clinic at the time of well-child visits from birth through 36 months, and...

To investigate the impact of social buffering on pain, the study team administered mild tail shocks to infant rat pups at postnatal day (PN) 8 or 12, with or without their mothers. They hypothesized that repeated exposure to shock would alter their inflammatory pain responses as adults when experienced between PN5 and 9 (pain sensitive period prior to functional maturation of the amygdala), whereas...

This dataset was collected for a study which examined differences in the gut microbiome within a cohort of 12-month old infants who provided samples either before the start of the COVID-19 pandemic or during the first 9 months of the pandemic. The study also assessed the demographics and health of the infants' primary caregivers, including factors such as race, ethnicity, socioeconomic status, mental...