The National Longitudinal Study of Adolescent Health (Add Health) is a longitudinal study of a nationally representative sample of adolescents in grades 7-12 in the United States during the 1994-1995 school year. Add Health combines longitudinal survey data on respondents' social, economic, psychological and physical well-being with contextual data on the family, neighborhood, community, school, friendships,...

The Women's Health Initiative (WHI) is a longitudinal national health study sponsored by the National Heart, Lung, and Blood Institute (NHLBI) that focuses on strategies for preventing heart disease, breast cancer, colorectal cancer, and osteoporotic fractures in postmenopausal women in the United States. The study includes data from 161,808 women aged 50-79 years old at the time of enrollment. Available...

The Nurses' Health Studies (NHS) are long-running, questionnaire-based studies on women's health. The study was initiated in 1976 with the NHS cohort. The initial studies focus on cancer, cardiovascular disease and risk factors for chronic health issues in women. The latest cohort, NH3, has been expanded to include both male and female registered nurses and nursing students. Survey and biospecimen...

The Jackson Heart Study (JHS) is a population-based longitudinal study based in Jackson, Mississippi that investigates risk factors for cardiovascular disease among African Americans. It is a collaborative research project by the University of Mississippi Medical Center, Jackson State University, and Tougaloo College. The primary objective is to investigate environmental and genetic factors associated...

Data from the ongoing NYU Women's Health Study include biospecimens and survey data with variables concerning health conditions, reproductive history, and dietary habits. Between 1985 and 1991, the NYU Women's Health Study enrolled 14,274 women between the ages of 35 and 65 years old at the Guttman Breast Diagnostic Institute in New York City for a study of endogenous hormones, diet, and risk of breast...

The Demographic and Health Surveys (DHS) Program overseen by the US Agency for International AID (USAID) uses nationally representative surveys, biomarker testing, and geographic location to collect data on monitoring and impact evaluation indicators for individual countries and for cross-country comparisons. Standardized DHS surveys include the Demographic and Health Survey, Service Provision Assessment,...

The Type 1 Diabetes (T1D) Exchange Clinic Registry collects information on individuals with type 1 diabetes from participating institutions in the United States in order to help researchers characterize individuals living with the disease, conduct exploratory or hypothesis-generating analyses, and identify potential participants for future clinical studies. The registry includes over 26,000 individuals...

The Osteoarthritis Initiative (OAI) was a longitudinal cohort study which investigated the natural history of knee osteoarthritis across the spectrum of the disease through the collection of imaging, biochemical, genetic, and risk markers of knee OA. Measures included knee symptoms and function (evaluated using the West Ontario and McMaster Universities Arthritis Index (WOMAC) and the Knee injury and...

This data was generated in a study to characterize brain bioenergetics in a cohort of clinically and cognitively normal women between the ages of 40 and 50 at different endocrine transition states including premenopause (n = 15), perimenopause (n = 14), and postmenopause (n = 14) in order to study the increased risk for Alzheimer’s disease in women. All subjects received clinical, laboratory, and neuropsychological...

This dataset was generated through a prospective randomized, double-blind study to determine the effects of serial phlebotomy on vascular endothelial function in the brachial artery. Subjects of the study were 84 iron-replete, non-anemia men and post-menopausal women age 40-70 years. Subjects were randomly assigned to three study treatment groups: Four serial phlebotomy procedures each followed by...