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NYU Dataset
Video and single cell recordings from a study of the role of oxytocin neurons in social transmission of maternal behavior among mice
- Authors
- Ioana CarceaRobert C. Froemke
- Description
Oxytocin, a hormone released by the hypothalamic paraventricular nucleus (PVN), enables neuroplasticity in the auditory cortex for maternal recognition of pup distress. This study continuously monitored the behavior of female virgin mice co-housed with an experienced mother and litter. To examine the behavioral events and neural activity patterns that lead to maternal behavior in virgin female mice,...
- Subject
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Neuroscience
- Access Rights
- Free to All
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NYU Dataset
Maternal Behavior in Mice Results From Intrinsic Mechanisms and Experience-Dependent Plasticity in Auditory Cortex
- Authors
- Jennifer K. SchiavoSilvana ValtchevaChloe J. Bair-MarshallSoomin C. Song2 more author(s)...
- Description
This study examined to what extent parental animals are intrinsically sensitive to neonatal vocalizations, or instead learn about vocal cues for parenting responses. In mice, naive virgins do not recognize the meaning of pup distress calls, but retrieve isolated pups to the nest following cohousing with a mother and litter. For this study, C57BL/6J virgin females were used in all experiments. The dataset...
- Subject
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Neuroscience
- Access Rights
- Free to All
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NYU Dataset
Heterosynaptic Plasticity Determines the Set-Point for Cortical Excitatory-Inhibitory Balance
- Authors
- Rachel E. FieldJames A. D’amourRobin TremblayChristoph Miehl3 more author(s)...
- Description
Cortical inhibitory and excitatory inputs are initially mismatched, but become balanced with experience during development. However, how excitatory-inhibitory balance is defined at most synapses, or the mechanisms for maintaining this balance at specific set-points is still unclear. This study demonstrated how coordinated long-term plasticity calibrates populations of excitatory/inhibitory inputs onto...
- Subject
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Neuroscience
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- Application RequiredAuthor Approval Required
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NYU Dataset
Locus Coeruleus Activity Improves Cochlear Implant Performance
- Authors
- Erin GlennonAngela ZhuYoussef Z. WadghiriMario A. Svirsky1 more author(s)...
- Description
Cochlear implant use require neuroplasticity within the central auditory system. Despite extensive studies on how cochlear implants activate the auditory system, understanding of cochlear implant-related neuroplasticity remains unknown. This study investigated behavioral responses and neural activity in locus coeruleus and auditory cortex of deafened rats fitted with multi-channel cochlear implants....
- Subject
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Neuroscience
- Access Rights
- Free to All
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NYU Dataset
Neural Circuitry for Maternal Oxytocin Release Induced by Infant Cries
- Authors
- Silvana ValtchevaHabon A. IssaChloe J. Bair-MarshallKathleen A. Martin4 more author(s)...
- Description
Oxytocin is a neuropeptide released in the central nervous system, which is involved in a wide range of behaviors including reproduction, parental care, and pair bonding. In addition, peripheral oxytocin is important for milk ejection during nursing and uterine contractions during labor. Oxytocin is produced mainly in the paraventricular nucleus (PVN) and supraoptic nucleus of the hypothalamus. This...
- Subject
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Neuroscience
- Access Rights
- Free to All
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NYU Dataset
Cortical Neuron Firing Patterns, Synaptic Connectivity, and Plasticity to Task Performance
- Authors
- Michele N. InsanallyBadr F. AlbannaJade TothBrian DePasquale6 more author(s)...
- Description
This study investigated the synaptic basis for various types of spiking response profiles, and how synaptic plasticity learning rules are important for shaping synaptic inputs for spike output and network performance. They leveraged cell-attached, extracellular, and whole-cell recordings from behaving animals alongside recurrent network modeling to explore the synaptic origins and functional contribution...
- Subject
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Neuroscience
- Access Rights
- Free to All