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  • NYU Dataset

    Video and single cell recordings from a study of the role of oxytocin neurons in social transmission of maternal behavior among mice

    Authors
    Ioana Carcea
    Robert C. Froemke
    Description

    Oxytocin, a hormone released by the hypothalamic paraventricular nucleus (PVN), enables neuroplasticity in the auditory cortex for maternal recognition of pup distress. This study continuously monitored the behavior of female virgin mice co-housed with an experienced mother and litter. To examine the behavioral events and neural activity patterns that lead to maternal behavior in virgin female mice,...

    Subject
    Neuroscience
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    Free to All
  • NYU Dataset

    Maternal Behavior in Mice Results From Intrinsic Mechanisms and Experience-Dependent Plasticity in Auditory Cortex

    Authors
    Jennifer K. Schiavo
    Silvana Valtcheva
    Chloe J. Bair-Marshall
    Soomin C. Song
    2 more author(s)...
    Description

    This study examined to what extent parental animals are intrinsically sensitive to neonatal vocalizations, or instead learn about vocal cues for parenting responses. In mice, naive virgins do not recognize the meaning of pup distress calls, but retrieve isolated pups to the nest following cohousing with a mother and litter. For this study, C57BL/6J virgin females were used in all experiments. The dataset...

    Subject
    Neuroscience
    Access Rights
    Free to All
  • NYU Dataset

    Heterosynaptic Plasticity Determines the Set-Point for Cortical Excitatory-Inhibitory Balance

    Authors
    Rachel E. Field
    James A. D’amour
    Robin Tremblay
    Christoph Miehl
    3 more author(s)...
    Description

    Cortical inhibitory and excitatory inputs are initially mismatched, but become balanced with experience during development. However, how excitatory-inhibitory balance is defined at most synapses, or the mechanisms for maintaining this balance at specific set-points is still unclear. This study demonstrated how coordinated long-term plasticity calibrates populations of excitatory/inhibitory inputs onto...

    Subject
    Neuroscience
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    Author Approval Required
  • NYU Dataset

    Locus Coeruleus Activity Improves Cochlear Implant Performance

    Authors
    Erin Glennon
    Angela Zhu
    Youssef Z. Wadghiri
    Mario A. Svirsky
    1 more author(s)...
    Description

    Cochlear implant use require neuroplasticity within the central auditory system. Despite extensive studies on how cochlear implants activate the auditory system, understanding of cochlear implant-related neuroplasticity remains unknown. This study investigated behavioral responses and neural activity in locus coeruleus and auditory cortex of deafened rats fitted with multi-channel cochlear implants....

    Subject
    Neuroscience
    Access Rights
    Free to All
  • NYU Dataset

    Neural Circuitry for Maternal Oxytocin Release Induced by Infant Cries

    Authors
    Silvana Valtcheva
    Habon A. Issa
    Chloe J. Bair-Marshall
    Kathleen A. Martin
    4 more author(s)...
    Description

    Oxytocin is a neuropeptide released in the central nervous system, which is involved in a wide range of behaviors including reproduction, parental care, and pair bonding. In addition, peripheral oxytocin is important for milk ejection during nursing and uterine contractions during labor. Oxytocin is produced mainly in the paraventricular nucleus (PVN) and supraoptic nucleus of the hypothalamus. This...

    Subject
    Neuroscience
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    Free to All
  • NYU Dataset

    Cortical Neuron Firing Patterns, Synaptic Connectivity, and Plasticity to Task Performance

    Authors
    Michele N. Insanally
    Badr F. Albanna
    Jade Toth
    Brian DePasquale
    6 more author(s)...
    Description

    This study investigated the synaptic basis for various types of spiking response profiles, and how synaptic plasticity learning rules are important for shaping synaptic inputs for spike output and network performance. They leveraged cell-attached, extracellular, and whole-cell recordings from behaving animals alongside recurrent network modeling to explore the synaptic origins and functional contribution...

    Subject
    Neuroscience
    Access Rights
    Free to All