Several spatial coding mechanisms are known to coexist in the hippocampus. However, how are they influenced by various environmental features is still unclear. This study investigated the spatial coding characteristics of hippocampal neurons in mice and rats navigating in different environments. C57BL/6 mice and Long-Evans rats were used in this study. For both mice and rats, most CA1 cells were recorded...

This study described a unique set of deep layer neurons in posterior parietal cortex (PPC) whose spiking activity is inversely correlated with all principal cells and interneurons in all brain states, but most commonly during the down state of non-REM (NREM) sleep. They identified down state-active (DSA) neurons as deep layer neocortical neurogliaform cells that express ID2 and Nkx2.1. For this study,...

This dataset is composed of eight bilateral silicon-probe multi-cellular electrophysiological recordings performed on four male Long-Evans rats. These recordings were performed to assess the effect of novel spatial learning on hippocampal CA1 neural firing and LFP patterns in naïve animals. Each session consisted of a long (~4 hour) PRE rest/sleep epoch home-cage recordings performed in a familiar...

This dataset contains recordings made using a silicon probe from three areas from a single rat that was performing different behavioral tasks. The three regions recorded from are left and right hippocampal CA1 and right entorhinal cortex. The tasks are a left/right alternate selection task, wheel running, and platform exploration. The neural data was recorded on 125 channels. In the study, five...

This dataset of multi single neuron recordings was acquired from three rats (EE, FF, GG) while they performed a working memory task. Neuronal activity was monitored simultaneously in the PFC (64 channels) and the intermediate CA1 (32 channels) of the hippocampus. In one rat (EE), sleep was also recorded before and after the task. The data was obtained during 52 main recording sessions and nine short...

Oxytocin, a hormone released by the hypothalamic paraventricular nucleus (PVN), enables neuroplasticity in the auditory cortex for maternal recognition of pup distress. This study continuously monitored the behavior of female virgin mice co-housed with an experienced mother and litter. To examine the behavioral events and neural activity patterns that lead to maternal behavior in virgin female mice,...

Electrophysiological recordings were obtained from male rats who were subjected to localized cooling of their medial septum (MS) prior to completing behavioral tasks. The MS is critical in theta generation. Therefore, temperature manipulation of the MS was used to test these models. Approximately 40 control trials were completed, followed by exposure to dry ice to reduce MS temperature for 20 to 60...

The Buzsáki Lab has shared designs for a 3D-printed metal microdrive and head cap system for freely-moving rodents and sample electrophysiological recordings. The modular design allows for recovery and reuse of silicon probes in multiple experiments with mice and Long-Evans rats. The .step files for the metal microdrive are optimized for stainless steel 316L in 20 micrometer resolution and aluminum...

The investigators collected behavioral data from two macaque monkeys (M1 and M2) who were presented with a direction discrimination task with post-decision wagering. These monkeys received prior training to report the net direction of motion of a set of randomly moving dots. In each trial, the subject fixed their gaze on an initial fixation point, then red dots would appear on the periphery of the...

Using a Y-shaped maze, several experiments were developed to assess conditions of associative learning among fruit fly larvae. Prior to the start of the experiments, some fruit fly larvae were fed a diet of all-trans-retinal (ATR), which is a co-factor for csChrimson activation (eliciting escape behavior in flies which perceive red light). A subgroup of larvae who were fed ATR also received cycloheximide...