The NYC Health and Nutritional Examination Survey (NYC HANES), modeled on the National Health and Nutrition Examination Survey (NHANES), is a population-based, cross-sectional study with data collected from physical examinations, clinical and laboratory tests, as well as face-to-face interviews and audio computer-assisted self-interviews (ACASI). It was first conducted in 2004 by the NYC Department...

The University of Michigan Health and Retirement Study (HRS) is a longitudinal panel study that surveys a representative sample of more than 26,000 Americans over the age of 50 every two years. The HRS explores the changes in labor force participation and the health transitions that individuals undergo toward the end of their work lives and in the years that follow, collecting information about income,...

The Framingham Heart Study (FHS) is an ongoing cohort study dedicated to identifying common factors or characteristics that contribute to cardiovascular disease (CVD). It is a collaborative project of the National Heart, Lung and Blood Institute and Boston University. In 1948, an original cohort of 5,209 men and women between 30 and 62 years old were recruited from Framingham, MA. An Offspring Cohort...

The Women's Health Initiative (WHI) is a longitudinal national health study sponsored by the National Heart, Lung, and Blood Institute (NHLBI) that focuses on strategies for preventing heart disease, breast cancer, colorectal cancer, and osteoporotic fractures in postmenopausal women in the United States. The study includes data from 161,808 women aged 50-79 years old at the time of enrollment. Available...

The Nurses' Health Studies (NHS) are long-running, questionnaire-based studies on women's health. The study was initiated in 1976 with the NHS cohort. The initial studies focus on cancer, cardiovascular disease and risk factors for chronic health issues in women. The latest cohort, NH3, has been expanded to include both male and female registered nurses and nursing students. Survey and biospecimen...

Action to Control Cardiovascular Risk in Diabetes (ACCORD) was a large clinical trial examining methods of lowering the rate of cardiovascular disease in adults with type two diabetes. The study was composed of three main clinical trials: an intensive lowering of blood sugar levels (Glycemia Trial), intensive lowering of blood pressure (Blood Pressure Trial), and treatment of multiple blood lipids...

Data from the ongoing NYU Women's Health Study include biospecimens and survey data with variables concerning health conditions, reproductive history, and dietary habits. Between 1985 and 1991, the NYU Women's Health Study enrolled 14,274 women between the ages of 35 and 65 years old at the Guttman Breast Diagnostic Institute in New York City for a study of endogenous hormones, diet, and risk of breast...

The Demographic and Health Surveys (DHS) Program overseen by the US Agency for International AID (USAID) uses nationally representative surveys, biomarker testing, and geographic location to collect data on monitoring and impact evaluation indicators for individual countries and for cross-country comparisons. Standardized DHS surveys include the Demographic and Health Survey, Service Provision Assessment,...

This dataset is a product of an investigation of microbe-metabolite relationships in the gut as a means to understand and potentially reduce colorectal cancer (CRC) risk. Microbiota and metabolomics profiling was performed on lyophilized feces from 42 colorectal cancer cases and 89 matched controls. Multivariable logistic regression was used to identify statistically independent associations with CRC....

The Osteoarthritis Initiative (OAI) was a longitudinal cohort study which investigated the natural history of knee osteoarthritis across the spectrum of the disease through the collection of imaging, biochemical, genetic, and risk markers of knee OA. Measures included knee symptoms and function (evaluated using the West Ontario and McMaster Universities Arthritis Index (WOMAC) and the Knee injury and...