NYU Dataset
Fecal Microbiota, Fecal Metabolome, and Colorectal Cancer Interrelations
UID: 10121
- Description
- This dataset is a product of an investigation of microbe-metabolite relationships in the gut as a means to understand and potentially reduce colorectal cancer (CRC) risk. Microbiota and metabolomics profiling was performed on lyophilized feces from 42 colorectal cancer cases and 89 matched controls. Multivariable logistic regression was used to identify statistically independent associations with CRC. First principal coordinate-component pair (PCo1-PC1) and false discovery rate (0.05)-corrected P-values were calculated for 116,000 Pearson correlations between 530 metabolites and 220 microbes in a sex*case/control meta-analysis. The dataset includes information on metabolites most strongly correlated with CRC-associated taxa by case-control status, and logistic regression association with CRC for the 72 metabolite-microbial taxon pairs that were correlated with each other at false discovery rate 0.05. Detailed information on methodology is available on figshare and in the Associated Publication.
Access
- Restrictions
-
Free to All
- Instructions
- The dataset may be accessed through the figshare repository.
Observational
- Grant Support
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