Action to Control Cardiovascular Risk in Diabetes Trial
Alternate Titles(s): ACCORD
- Description
Action to Control Cardiovascular Risk in Diabetes (ACCORD) was a large clinical trial examining methods of lowering the rate of cardiovascular disease in adults with type two diabetes. The study was composed of three main clinical trials: an intensive lowering of blood sugar levels (Glycemia Trial), intensive lowering of blood pressure (Blood Pressure Trial), and treatment of multiple blood lipids with a combination of a fibrate and a statin (Lipid Therapy Trial). There were two ancillary trials: an evaluation of ACCORD interventions on patients with diabetic retinopathy (EYE Substudy) and an evaluation of ACCORD interventions to improve glycemic control on the adverse effects of type 2 diabetes on the brain (MIND Substudy).
The study began in 1999 and recruited at total of 10,251 adults with type 2 diabetes and HbA1c concentrations of at least 7.5%.
- Publisher
- Timeframe
- 2001 - 2009
- Geographic Coverage
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CanadaUnited States
- Local Expert
Access
- Restrictions
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Application Required
- Instructions
- Researchers can apply to use ACCORD data and request biospecimens through the BioLINCC repository (registration required) by submitting a protocol for an ancillary study. An ACCORD principal investigator or co-investigator must be included as the PI or co-investigator on an ancillary study. All ancillary studies must be reviewed and approved to access data. Proposals should be submitted at least 60 days before a funding application deadline to assure timely approval.
- PubMed Search
- View articles which use this dataset
- Other Resources
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ClinicalTrials.gov
NCT00000620