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Results Found: 269
  • NYU Dataset

    3D-printable model and electrophysiological recordings for a headgear system for freely-moving rodents

    Authors
    Mihaly Voroslakos
    Peter C. Petersen
    Balázs Vöröslakos
    Gyorgy Buzsaki
    Description

    The Buzsáki Lab has shared designs for a 3D-printed metal microdrive and head cap system for freely-moving rodents and sample electrophysiological recordings. The modular design allows for recovery and reuse of silicon probes in multiple experiments with mice and Long-Evans rats. The .step files for the metal microdrive are optimized for stainless steel 316L in 20 micrometer resolution and aluminum...

    Subject
    Neuroscience
    Access Rights
    Free to All
  • NYU Dataset

    A Dedicated Hypothalamic Oxytocin Circuit Controls Aversive Social Learning

    Authors
    Takuya Osakada
    Rongzhen Yan
    Yiwen Jiang
    Dongyu Wei
    9 more author(s)...
    Description

    Fighting is a major means to compete for limited resources in the wild. After the fight ends, the loser continuously avoids close interaction with the winner and readily flees when confronted. The neural mechanisms that underlie the rapid and long-lasting behavioral changes induced by defeat remains unclear. This study identified oxytocin neurons in the retrochiasmatic supraoptic nucleus and oxytocin-receptor-expressing...

    Subject
    Neuroscience
    Access Rights
    Free to All
  • AHRQ Social Determinants of Health Database

    Alternate Title(s)
    AHRQ SDOH Database
    Description

    The Social Determinants of Health (SDOH) Database was created by the Agency for Healthcare Research and Quality (AHRQ) with funding from the Patient Centered Outcomes Research (PCOR) Trust Fund to enable research with linkable SDOH-focused data derived from multiple sources and across multiple domains. Since the data is compiled from multiple sources, users are advised to consult the associated documentation...

    Subject
    Population Characteristics
    Risk Factors
    Access Rights
    Free to All
    Local Expert
    Population Health Data Hub
  • NYU Dataset

    Action-Driven Remapping of Hippocampal Neuronal Populations in Jumping Rats

    Authors
    Laura Green
    David Tingley
    John Rinzel
    Gyorgy Buzsaki
    Description

    Hippocampus plays a key role in navigation guided by environmental inputs. However, a critical aspect of navigation is a sequence of planned and coordinated actions. This study investigated the role of action in the neuronal organization of the hippocampus by training rats to jump a gap on a linear track. For this study, Long-Evans rats were used for recording local field potentials and ensembles of...

    Subject
    Neuroscience
    Access Rights
    Free to All
  • NYU Dataset

    Adipose Tissue Macrophages Adapt to Inflammatory and Metabolic Challenges

    Authors
    Hernandez Moura Silva
    Andre Bafica
    Gabriela Flavia Rodrigues-Luiz
    Jingyi Chi
    13 more author(s)...
    Description

    Adipose tissue macrophages (ATMs) change during metabolic stress and are thought to contribute to metabolic syndrome. This study examined ATM subpopulations in steady state and in response to nutritional and infectious challenges. They characterized the epididymal white adipose tissue (eWAT) lymphoid and myeloid cell populations under steady state using RNA sequencing to analyze the transcriptome of...

    Subject
    Genomics
    Access Rights
    Free to All
  • NYU Dataset

    Aggregation‐Seeding Forms of α‐Synuclein Are Not Detected in Acute Coronavirus Disease 2019 Cerebrospinal Fluid

    Authors
    Marco J. Russo
    Karen MacLeod
    Jennifer Lamoureux
    Russ Lebovitz
    5 more author(s)...
    Description

    To investigate whether acute SARS‐CoV‐2 infection was associated with (1) amyloidogenic, aggregation‐prone forms of αSyn in the cerebrospinal fluid (CSF), (2) signature of pathogenic changes, and (3) future risk for frank synucleinopathy, the research team compared CSF biomarkers obtained through lumbar puncture for the evaluation of neurologic symptoms from 12 adult patients hospitalized at NYU Langone...

    Subject
    COVID-19
    Infectious Disease
    Neuroscience
    Risk Factors
    Access Rights
    Free to All
  • Allen Mouse Brain Atlas

    Description

    The Allen Mouse Brain Atlas is a three-dimensional atlas of gene expression throughout the adult mouse brain. The atlas is separated into four key features:In Situ Hybridization (ISH) Data includes image data with cellular level resolution. To find gene expression data, search can be performed using Gene Search, Differential Search, Fine Structure Search, Bulk Search, and Human Differential Search.Reference...

    Access Rights
    Free to All
    Local Expert
    Jiangyang Zhang
    Zifei Liang
  • Alzheimer’s Disease Neuroimaging Initiative

    Alternate Title(s)
    ADNI, ADNI1, ADNI GO, ADNI2, ADNI3
    Authors
    Michael W. Weiner
    Description

    The Alzheimer’s Disease Neuroimaging Initiative (ADNI) began in 2004 as longitudinal multicenter study to identify clinical, imaging, genetic, and biochemical biomarkers for the detection and tracking of Alzheimer’s disease (AD). Participants are recruited from and followed at 59 research sites in the United States and Canada. ADNI1 enrolled 400 subjects who were diagnosed with mild cognitive impairment...

    Subject
    Chronic Disease
    Genomics
    Mental Health
    Neuroscience
    Access Rights
    Free to All
    Application Required
    Author Approval Required
    Local Expert
    Omonigho M. Bubu
    Ricardo Osorio
  • American Community Survey

    Alternate Title(s)
    ACS
    Description

    The American Community Survey (ACS) is an ongoing annual survey that publishes and collects data on the population of the United States. The survey is issued to approximately 3.5 million households per year. The ACS contains detailed questions assessing social, economic, demographic, and housing characteristics, including age, sex, race, family and relationships, income and benefits, health insurance,...

    Subject
    Health Status
    Population Characteristics
    Access Rights
    Free to All
    Local Expert
    Ben Spoer
  • American Time Use Survey

    Alternate Title(s)
    ATUS
    Description

    The American Time Use Survey (ATUS) is an annual survey which provides nationally representative estimates of how, where, and with whom Americans aged 15 years old and up spend their time. It is the only federal survey providing data on the full range of nonmarket activities, from childcare to volunteering.

    Subject
    Population Characteristics
    Access Rights
    Free to All