The Buzsáki Lab has shared designs for a 3D-printed metal microdrive and head cap system for freely-moving rodents and sample electrophysiological recordings. The modular design allows for recovery and reuse of silicon probes in multiple experiments with mice and Long-Evans rats. The .step files for the metal microdrive are optimized for stainless steel 316L in 20 micrometer resolution and aluminum...

Hippocampus plays a key role in navigation guided by environmental inputs. However, a critical aspect of navigation is a sequence of planned and coordinated actions. This study investigated the role of action in the neuronal organization of the hippocampus by training rats to jump a gap on a linear track. For this study, Long-Evans rats were used for recording local field potentials and ensembles of...

The Allen Mouse Brain Atlas is a three-dimensional atlas of gene expression throughout the adult mouse brain. The atlas is separated into four key features:In Situ Hybridization (ISH) Data includes image data with cellular level resolution. To find gene expression data, search can be performed using Gene Search, Differential Search, Fine Structure Search, Bulk Search, and Human Differential Search.Reference...

The Alzheimer’s Disease Neuroimaging Initiative (ADNI) began in 2004 as longitudinal multicenter study to identify clinical, imaging, genetic, and biochemical biomarkers for the detection and tracking of Alzheimer’s disease (AD). Participants are recruited from and followed at 59 research sites in the United States and Canada. ADNI1 enrolled 400 subjects who were diagnosed with mild cognitive impairment...

The American Community Survey (ACS) is an ongoing annual survey that publishes and collects data on the population of the United States. The survey is issued to approximately 3.5 million households per year. The ACS contains detailed questions assessing social, economic, demographic, and housing characteristics, including age, sex, race, family and relationships, income and benefits, health insurance,...

The American Time Use Survey (ATUS) is an annual survey which provides nationally representative estimates of how, where, and with whom Americans aged 15 years old and up spend their time. It is the only federal survey providing data on the full range of nonmarket activities, from childcare to volunteering.

Gene expression rapidly responds to physiological stress like virus infection in part via the control of mRNA translation. However, how translation of virus and host mRNAs are regulated during infection stress remains unknown. This study showed that protein synthesis in human cytomegalovirus (HCMV)-infected cells unexpectedly becomes progressively reliant upon eIF3d, which is a mRNA cap-binding protein...

This is a retrospective cohort study of COVID-19 hospitalized patients with different degrees of severity. They performed this study to analyze the generation of autoimmune antibodies to common antigens. This study included 115 hospitalized cases of SARS-CoV-2 infection and 42 uninfected controls. Sample collection was performed as part of routine clinical care for COVID-19 patients at the time of...

The Area Health Resources Files (AHRF) provides current as well as historic data for more than 6,000 variables for each of the nation's counties, as well as state and national data. It contains information on health facilities, health professions, measures of resource scarcity, health status, economic activity, health training programs, and socioeconomic and environmental characteristics. In addition,...

The Assessment Capacities Project (ACAPS) Government Measures dataset is an active tracker of government responses to the pandemic over time as compiled by ACAPS analysts and volunteers from the University of Copenhagen and University of Lund. Information is obtained from public sources, including governments, media, United Nations agencies, and other organizations, and are denoted in the dataset. Government...