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  • NYU Dataset

    Video and single cell recordings from a study of the role of oxytocin neurons in social transmission of maternal behavior among mice

    Authors
    Ioana Carcea
    Robert C. Froemke
    Description

    This dataset includes video recordings of the behavior of virgin mice with dams and pups and single cell recordings from the left paraventricular hypothalamic nucleus of virgin mice. The associated study examined neural activation related to the acquisition of pup retrieval behavior as virgin mice were enlisted in maternal care by experienced mothers. In the study, C57B1/6 virgin female mice were...

    Subject
    Neuroscience
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    Free to All
  • NYU Dataset

    Maternal Behavior in Mice Results From Intrinsic Mechanisms and Experience-Dependent Plasticity in Auditory Cortex

    Authors
    Jennifer K. Schiavo
    Silvana Valtcheva
    Chloe J. Bair-Marshall
    Soomin C. Song
    2 more author(s)...
    Description

    This study examined to what extent parental animals are intrinsically sensitive to neonatal vocalizations, or instead learn about vocal cues for parenting responses. In mice, naive virgins do not recognize the meaning of pup distress calls, but retrieve isolated pups to the nest following cohousing with a mother and litter. For this study, C57BL/6J virgin females were used in all experiments. The dataset...

    Subject
    Neuroscience
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    Free to All
  • NYU Dataset

    Oxytocin Alters Intrinsic Properties of CA2 Pyramidal Cells to Induce Burst Firing

    Authors
    Natasha N. Tirko
    Katherine W. Eyring
    Ioana Carcea
    Mariela Mitre
    3 more author(s)...
    Description

    This study described robust oxytocinergic modulation of intrinsic properties and circuit operations in hippocampal area CA2. For this study, male mice were used for all experiments to avoid variation in oxytocin receptor (OXTR) expression throughout the estrous cycle of female mice. C57BL/6 mice were used in wild-type experiments, while homozygous Oxt-IRES-Cre and hemizygote Amigo2-Cre mice were used...

    Subject
    Neuroscience
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  • NYU Dataset

    Neural Circuitry for Maternal Oxytocin Release Induced by Infant Cries

    Authors
    Silvana Valtcheva
    Habon A. Issa
    Chloe J. Bair-Marshall
    Kathleen A. Martin
    4 more author(s)...
    Description

    Oxytocin is a neuropeptide released in the central nervous system, which is involved in a wide range of behaviors including reproduction, parental care, and pair bonding. In addition, peripheral oxytocin is important for milk ejection during nursing and uterine contractions during labor. Oxytocin is produced mainly in the paraventricular nucleus (PVN) and supraoptic nucleus of the hypothalamus. This...

    Subject
    Neuroscience
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  • NYU Dataset

    A Dedicated Hypothalamic Oxytocin Circuit Controls Aversive Social Learning

    Authors
    Takuya Osakada
    Rongzhen Yan
    Yiwen Jiang
    Dongyu Wei
    9 more author(s)...
    Description

    Fighting is a major means to compete for limited resources in the wild. After the fight ends, the loser continuously avoids close interaction with the winner and readily flees when confronted. The neural mechanisms that underlie the rapid and long-lasting behavioral changes induced by defeat remains unclear. This study identified oxytocin neurons in the retrochiasmatic supraoptic nucleus and oxytocin-receptor-expressing...

    Subject
    Neuroscience
    Access Rights
    Free to All