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NYU Dataset
Sequencing Data for a Delta-Omicron Recombinant in an Immunosuppressed Transplant Recipient Treated with Monoclonal Antibody Sotrovimab
- Authors
- Ralf DuerrHao ZhouTakuya TadaDacia Dimartino18 more author(s)...
- Description
A Delta-Omicron recombinant of the SARS-CoV-2 virus was sequenced and isolated from an immunosuppressed and unvaccinated male kidney transplant patient who received Sotrovimab for treatment of COVID-19. Further clinical details and medical history of the patient are described in the associated publication. Sotrovimab is a therapeutic monoclonal antibody (mAb) used to treat infections by the BA.1 Omicron...
- Subject
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COVID-19GenomicsInfectious Disease
- Timeframe
- 2022
- Access Rights
- Free to AllApplication Required
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NYU Dataset
RNA and TCR Sequencing Characterized Cytotoxic T Cells and TCR Clonality in Organ Transplant Recipients with Squamous Cell Carcinoma
- Authors
- Nicholas FrazzetteAlireza Khodadadi-JamayranNicole DoudicanAlexis Santana4 more author(s)...
- Description
This dataset was collected to show that there is a decline in cytotoxic T cells and TCR clonality in organ transplant recipients (OTRs) with squamous cell carcinoma (SCC). In this study, 5 SCC tumor samples and 6 transplant-associated SCC (TSCC) tumor samples were analyzed. Among SCC samples, the male to female ratio was 3 to 2 and the mean patient age was 81 years. Among TSCC samples, the male to...
- Subject
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CancerGenomicsSurgery
- Access Rights
- Free to All
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NYU Dataset
Outcomes of Breast Cancer Patients Treated with Chemotherapy, Biologic Therapy, Endocrine Therapy, or Active Surveillance During the COVID-19 Pandemic
- Authors
- Douglas K. MarksNibash BudhathokiJohn KucharczykFaisal Fa'ak20 more author(s)...
- Description
Data was abstracted from NYU Langone Health electronic health records, the Perlmutter Cancer Center Data Hub, and the NYU Langone Health SARS-CoV-2 Data Mart for all patients treated for breast cancer at Perlmutter Cancer Center either through telemedicine or in-person between February 1, 2020 and May 1, 2020 to determine the incidence of SARS-CoV-2 infection associated with treatment with cytotoxic...
- Timeframe
- 2020
- Access Rights
- Application RequiredAuthor Approval Required
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NYU Dataset
KEAP1 Mutation in Lung Adenocarcinoma Promotes Immune Evasion and Immunotherapy Resistance
- Authors
- Anastasia-Maria ZavitsanouRay PillaiYuan HaoWarren L. Wu23 more author(s)...
- Description
Lung cancer is the leading cause of cancer related deaths worldwide and immunotherapy has become an important therapeutic intervention. Immunotherapy for lung cancer patients often fails with specific mutations like KEAP1. This study examined the impact of KEAP1 mutations on cancer growth and immune surveillance. They generated an orthotopic transplant model of KrasG12D/+; p53-/- lung cancer with cells...
- Subject
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CancerGenomics
- Access Rights
- Free to All
