NYU Data Catalog

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Results Found: 6

  • Neurofibroma (NF) Registry

    Alternate Title(s)
    NF Registry
    Description

    This data contains information on patients with neurofibromatosis type 1 and neurofibromatosis type 2 and schwannomatosis. The neurofibromatoses (NF) are rare disorders with variation in clinical manifestations, and the NF Registry was created to assist researchers in studying the disease. Patients are included in the registry if they meet the diagnostic criteria for one of the three NF conditions....

    Subject
    Cancer
    Chronic Disease
    Health Status
    Neuroscience
    Risk Factors
    Access Rights
    Application Required
  • NYU Dataset

    RNA and TCR Sequencing Characterized Cytotoxic T Cells and TCR Clonality in Organ Transplant Recipients with Squamous Cell Carcinoma

    Authors
    Nicholas Frazzette
    Alireza Khodadadi-Jamayran
    Nicole Doudican
    Alexis Santana
    4 more author(s)...
    Description

    This dataset was collected to show that there is a decline in cytotoxic T cells and TCR clonality in organ transplant recipients (OTRs) with squamous cell carcinoma (SCC). In this study, 5 SCC tumor samples and 6 transplant-associated SCC (TSCC) tumor samples were analyzed. Among SCC samples, the male to female ratio was 3 to 2 and the mean patient age was 81 years. Among TSCC samples, the male to...

    Subject
    Cancer
    Genomics
    Surgery
    Access Rights
    Free to All
  • NYU Dataset

    Gene Expression and Transcription Factors are Modified in Human Keratinocytes Exposed to Solar Simulated Ultraviolet Radiation

    Authors
    Thomas L. Des Marais
    Thomas Kluz
    Dazhong Xu
    Xiaoru Zhang
    4 more author(s)...
    Description

    Ultraviolet radiation (UVR) from the sun is the major cause of skin cancer. However, genes and pathways altered by solar-simulated UVR (ssUVR), a mixture of UVA and UVB, still remains unclear. For this study, human HaCaT keratinocytes were exposed to a single dose or 5 repetitive doses of ssUVR. Analyses of gene expression profiles and functional annotation were performed at 24 hours after irradiation....

    Subject
    Cancer
    Genomics
    Access Rights
    Free to All
  • NYU Dataset

    Melanoma Clinicopathological-Biospecimen Database and Repository

    Authors
    Iman Osman
    Description

    Since 2002, the Interdisciplinary Melanoma Cooperative Group (IMCG) at Perlmutter Cancer Center has maintained one of the largest clinicopathologic resources, the Melanoma Clinicopathological-Biospecimen Database and Repository, for research on patients 18 years old and over with melanoma or at high risk for melanoma. Clinical data is stored in a secure REDCap database which contains 653 fields to...

    Subject
    Cancer
    Chronic Disease
    Genomics
    Risk Factors
    Access Rights
    Application Required
    Author Approval Required
  • NYU Dataset

    NR2F2 Isoform Unleashes a Metastatic Program in Melanoma

    Authors
    Veronica Davalos
    Claudia D. Lovell
    Richard Von Itter
    Igor Dolgalev
    17 more author(s)...
    Description

    This study described DNA methylation changes that accompany metastatic progression in melanoma patients and found localized methylation changes in the regulatory region of NR2F2. NR2F2 is an orphan-nuclear receptor that is essential for embryonic and neural crest cell (NCC) development. For this study, they examined DNA methylation profiles of NCCs and melanocytes as well as melanoma patient tissues...

    Subject
    Cancer
    Genomics
    Access Rights
    Free to All
  • NYU Dataset

    Mapping the Landscape of Histomorphological Cancer Phenotypes Using Self-Supervised Learning on Unannotated Pathology Slides

    Authors
    Adalberto Claudio Quiros
    Nicolas Coudray
    Anna H. Yeaton
    Xinyu Yang
    12 more author(s)...
    Description

    Histomorphological Phenotype Learning (HPL) was developed as a self-supervised methodology to discriminatory features in microscopy images to aid in cancer diagnosis and management. The methodology partitions whole slide images (WSIs) into meaningful Histomorphological Phenotype Clusters (HPCs) that can be used to define and quantify morphological phenotypes which recur within and between cases. HPL...

    Subject
    Cancer
    Chronic Disease
    Access Rights
    Free to All
    Author Approval Required