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  • NYU Dataset

    fastMRI

    Authors
    Florian Knoll
    Patricia M. Johnson
    Daniel K. Sodickson
    Michael P. Recht
    1 more author(s)...
    Description

    This deidentified imaging dataset is comprised of raw k-space data in several sub-dataset groups. Raw and DICOM data have been deidentified via conversion to the vendor-neutral ISMRMRD format and the RSNA Clinical Trial Processor, respectively. Manual inspection of each DICOM image was also performed to check for the presence of any unexpected protected health information (PHI), with spot checking...

    Subject
    Anatomy
    Cancer
    Access Rights
    Free to All
    Application Required
  • NYU Dataset

    Identification of PIM1 Substrates Reveals a Role for NDRG1 Phosphorylation in Prostate Cancer

    Authors
    Russell J. Ledet
    Sophie E. Ruff
    Yu Wang
    Shruti Nayak
    4 more author(s)...
    Description

    This study performed a chemical genetic screen to identify PIM1 substrates in prostate cancer cells. They identified 25 previously unknown PIM1 substrates and their phosphorylation sites. Among the identified PIM1 substrates, N-Myc Downstream-Regulated Gene 1 (NDRG1) was shown to be as an inhibitor of metastasis. The study demonstrated that PIM1 phosphorylation of NDRG1 reduced its stability, nuclear...

    Subject
    Cancer
    Proteomics
    Access Rights
    Free to All