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  • NYU Dataset

    Multi-unit spiking activity recorded from rat frontal cortex

    Alternate Title(s)
    FCX-1
    Authors
    Brendon O. Watson
    Daniel Levenstein
    J. Palmer Greene
    Jennifer N. Gelinas
    1 more author(s)...
    Description

    This data contains recordings from the rat frontal cortex (brain regions mPFC, OFC, ACC, and M2) during wake-sleep episodes where at least 7 minutes of wakefulness are followed by 20 minutes of sleep. The data was recorded using silicon probe electrodes in the frontal cortices of male Long Evans rats between 4-7 months of age during no specific behavior, task or stimulus. The animal was left alone...

    Subject
    Neurosciences
    Access Rights
    Free to All
  • NYU Dataset

    Brain-Wide Interactions During Hippocampal Sharp Wave Ripples

    Authors
    Noam Nitzan
    Rachel Swanson
    Dietmar Schmitz
    Gyorgy Buzsaki
    Description

    Many experiments have characterized the bidirectional relationship between sharp wave ripples (SPW-Rs) and activity in chosen brain areas. However, the topographic relationship between different segments of the hippocampus and brain-wide target areas has not been studied at high temporal and spatial resolution. This study analyzed two publicly available datasets with simultaneous high-density silicon...

    Subject
    Neurosciences
    Access Rights
    Free to All
  • NYU Dataset

    Routing of Hippocampal Ripples to Subcortical Structures via the Lateral Septum

    Authors
    David Tingley
    Gyorgy Buzsaki
    Description

    The function of hippocampal sharp-wave ripples (SPW-Rs) relate to the consolidation of recent experiences and planning of future actions. This study investigated the impact of SPW-Rs on the firing patterns of lateral septal (LS) neurons in behaving rats. The experiments were performed on Long-Evans rats. For this study, they examined the hippocampal-LS circuit by simultaneously recording activity patterns...

    Subject
    Neurosciences
    Access Rights
    Free to All
  • NYU Dataset

    Forty-Hertz Light Stimulation Does Not Entrain Native Gamma Oscillations in Alzheimer’s Disease

    Authors
    Marisol Soula
    Alejandro Martin-Avila
    Yiyao Zhang
    Annika Dhingra
    4 more author(s)...
    Description

    Alzheimer’s disease (AD) is characterized by abnormal aggregation of the proteins amyloid-β (Aβ). Recent studies showed that 40-Hz sensory stimulation is a potential treatment in AD. This study examined whether 40-Hz flickering light entrains gamma oscillations and suppresses Aβ in the brains of APP/PS1 and 5xFAD mouse models. For the study, they investigated the effect of 40-Hz light stimulation on...

    Subject
    Neurosciences
    Access Rights
    Free to All