Filter by
-
NYU Dataset
Chronic Stress Primes Innate Immune Responses in Mice and Humans
- Authors
- Tessa J. BarrettEmma M. CorrCoen van SolingenFlorencia Schlamp18 more author(s)...
- Description
Psychological stress is linked with systemic inflammation. It accelerates inflammatory disease progression and monocytes are key in sustaining systemic inflammation. However, the mechanisms underlying stress-mediated inflammation and future health risk remains unknown. This study examined the impact of psychological stress on monocytes and showed that psychological stress induces remodeling of the...
- Subject
-
Genomics
- Access Rights
- Free to All
-
NYU Dataset
Adipose Tissue Macrophages Adapt to Inflammatory and Metabolic Challenges
- Authors
- Hernandez Moura SilvaAndre BaficaGabriela Flavia Rodrigues-LuizJingyi Chi13 more author(s)...
- Description
Adipose tissue macrophages (ATMs) change during metabolic stress and are thought to contribute to metabolic syndrome. This study examined ATM subpopulations in steady state and in response to nutritional and infectious challenges. They characterized the epididymal white adipose tissue (eWAT) lymphoid and myeloid cell populations under steady state using RNA sequencing to analyze the transcriptome of...
- Subject
-
Genomics
- Access Rights
- Free to All
-
NYU Dataset
Single-Cell Analysis of Localized Prostate Cancer
- Authors
- Victor R. Adorno FeblesYuan HaoAarif AhsanJiansheng Wu18 more author(s)...
- Description
Prostate cancer (PCa) is the most common cancer diagnosis among men in the United States. This study characterized the tumor immune microenvironment of localized PCa, including high-grade prostate cancer (HGPCa) and low-grade prostate cancer (LGPCa) through single-cell RNA sequencing and multicolor flow cytometry of freshly isolated prostatectomy specimens. PCa tumor samples were collected from patients...
- Subject
-
CancerGenomics
- Access Rights
- Application RequiredAuthor Approval Required