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  • Bone marrow microenvironments that contribute to patient outcomes in newly diagnosed multiple myeloma

    Authors
    Samuel A. Danziger
    Mark McConnell
    Jake Gockley
    Mary H. Young
    29 more author(s)...
    Description

    This dataset contains data on the tumor microenvironment from the whole bone marrow of 436 patients who were diagnosed with multiple myeloma and enrolled in the interventional Total Therapy trial series conducted by the University of Arkansas for Medical Sciences. 266 male and 170 female patients were enrolled between February 25, 2004 and January 11, 2014 and completed 25 to 5,241 days of follow-up...

    Subject
    Cancer
    Chronic Disease
    Genomics
    Access Rights
    Free to All
    Local Expert
    Gareth J. Morgan
  • NYU Dataset

    SARS-CoV-2 infection triggers pro-atherogenic inflammatory responses in human coronary vessels

    Authors
    Natalia Eberhardt
    Maria G. Noval
    Ravneet Kaur
    Letizia Amadori
    19 more author(s)...
    Description

    This study combined multiple techniques (e.g., RNAscope in-situ hybridization, immunohistochemistry, immunofluorescence, single-cell RNA sequencing, bulk RNA sequencing, and functional assays) to investigate the inflammatory response associated with SARS-CoV-2 infection in human vascular tissues. Single cell RNA-sequencing data obtained from samples collected for this study is available via the Gene...

    Subject
    COVID-19
    Infectious Disease
    Risk Factors
    Access Rights
    Free to All
  • NYU Dataset

    Mapping the Landscape of Histomorphological Cancer Phenotypes Using Self-Supervised Learning on Unannotated Pathology Slides

    Authors
    Adalberto Claudio Quiros
    Nicolas Coudray
    Anna H. Yeaton
    Xinyu Yang
    12 more author(s)...
    Description

    Histomorphological Phenotype Learning (HPL) was developed as a self-supervised methodology to discriminatory features in microscopy images to aid in cancer diagnosis and management. The methodology partitions whole slide images (WSIs) into meaningful Histomorphological Phenotype Clusters (HPCs) that can be used to define and quantify morphological phenotypes which recur within and between cases. HPL...

    Subject
    Cancer
    Chronic Disease
    Access Rights
    Free to All
    Author Approval Required