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NYU Dataset
Switch-like and persistent memory formation in individual Drosophila larvae
- Authors
- Amanda LesarJavan TahirJason WolkMarc Gershow
- Description
Using a Y-shaped maze, several experiments were developed to assess conditions of associative learning among fruit fly larvae. Prior to the start of the experiments, some fruit fly larvae were fed a diet of all-trans-retinal (ATR), which is a co-factor for csChrimson activation (eliciting escape behavior in flies which perceive red light). A subgroup of larvae who were fed ATR also received cycloheximide...
- Subject
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Neuroscience
- Access Rights
- Free to All
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NYU Dataset
Behavioral and Electrophysiology Data Indicates Wind Direction is Decoded by Central Neurons in Drosophila
- Authors
- Marie P. SuverAndrew M. M. MathesonSinekdha SarkarMatthew Damiata2 more author(s)...
- Description
Wind is a major navigational cue for insects and this study examined how wind direction is decoded by central neurons in the insect brain. They determined that flies combine signals from both antennae to orient to wind during olfactory search behavior. In Drosophila, movements of the antennae are detected by mechanosensory neurons, known as Johnston’s Organ (JO) neurons. The JO neurons project from...
- Subject
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Neuroscience
- Access Rights
- Free to All
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NYU Dataset
Electrophysiology and Imaging Data Identified Central Complex Neurons that Encode Airflow Direction in Drosophila
- Authors
- Timothy A. CurrierAndrew M. M. MathesonKatherine I. Nagel
- Description
This data was collected to identify the brain regions and circuit organizations that support navigation. In insects, the central complex (CX) is thought to control many aspects of navigation. The CX is a highly organized neuropil, which consists of the protocerebral bridge, the ellipsoid body, the fan-shaped body, and the paired noduli. This study contains electrophysiology, imaging, and behavioral...
- Subject
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Neuroscience
- Access Rights
- Free to All
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NYU Dataset
Predicting Behavioral Dynamics in Drosophila Using Algorithms
- Authors
- Timothy A. CurrierKatherine I. Nagel
- Description
The algorithms used by the nervous system to integrate synergistic and conflicting stimuli across modalities are still under investigation. This study developed a closed-loop orienting paradigm in Drosophila to study the algorithms by which cues from two modalities are integrated during ongoing behavior. In the study, all experiments were performed on adult female flies three to five days after hatching....
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- Free to All
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NYU Dataset
Neurons Specify Goal-Directed Navigation Behaviors
- Authors
- Andrew M. M. MathesonAaron J. LanzAshley M. MedinaAl M. Licata3 more author(s)...
- Description
Animals frequently combine odor cues about source identity with wind direction cues about source location to navigate towards a food source. However, where and how these two cues are integrated to support navigation remains unknown. This study described a pathway to the Drosophila fan-shaped body that encodes attractive odor and promotes upwind navigation. Behavioral experiments were performed in a...
- Subject
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Neuroscience
- Access Rights
- Free to All
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NYU Dataset
Drosophila Fatty Acid Binding Protein Essential for Light-Dependent Rhodopsin-1 Degradation and Photoreceptor Survival
- Authors
- Huai-Wei HuangHyung Don Ryoo
- Description
Rhodopsins are light-detecting proteins associated with retinal chromophores. Dysfunctional Rhodopsins cause retinal degeneration in humans and model organisms. However, the mechanisms by which photoreceptors regulate Rhodopsin homeostasis remains unknown. This study performed a photoreceptor-specific gene expression profiling analysis to examine how photoreceptors respond to stress. For their investigation,...
- Subject
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Genomics
- Access Rights
- Free to All