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NYU Dataset
Fecal Microbiota, Fecal Metabolome, and Colorectal Cancer Interrelations
- Authors
- Rashmi SinhaJiyoung AhnJoshua N. SampsonJianxin Shi4 more author(s)...
- Description
This dataset is a product of an investigation of microbe-metabolite relationships in the gut as a means to understand and potentially reduce colorectal cancer (CRC) risk. Microbiota and metabolomics profiling was performed on lyophilized feces from 42 colorectal cancer cases and 89 matched controls. Multivariable logistic regression was used to identify statistically independent associations with CRC....
- Subject
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Cancer
- Access Rights
- Free to All
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NYU Dataset
Gut microbiome dysbiosis in antibiotic-treated COVID-19 patients is associated with microbial translocation and bacteremia
- Authors
- Lucie Bernard-RaichonMericien VenzonJon KleinJordan E. Axelrad21 more author(s)...
- Description
To investigate the relationship between gut microbiome dysbiosis and translocation of bacteria into the blood during SARS-CoV-2 infection in humans, researchers obtained blood culture and stool samples from positive COVID-19 patients who were seen at NYU Langone Health and Yale New Haven Hospital. 67 stool samples were obtained from 60 patients at NYU Langone Health and 63 samples were obtained from...
- Subject
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COVID-19GenomicsInfectious DiseaseRisk Factors
- Timeframe
- 2020
- Access Rights
- Free to All
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NYU Dataset
SARS-CoV-2 infection and gut microbiome dysbiosis in mice
- Authors
- Lucie Bernard-RaichonMericien VenzonJon KleinJordan E. Axelrad21 more author(s)...
- Description
To investigate the causal relationship between SARS-CoV-2 infection and gut microbiome dysbiosis, researchers inoculated K18-hACE2 male mice with one of four doses (10, 100, 1000, and 104 PFU) of SARS-CoV-2 or mock treatment diluted in phosphate-buffered saline (PBS). Fecal samples were collected from mice daily for microbiome analyses from day 0 (before infection) until sacrifice on days 5–7. Upon...
- Subject
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COVID-19GenomicsInfectious Disease
- Access Rights
- Free to All
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NYU Dataset
Isolation of Clostridia from the Gut Microbiome of Helminth-Colonized Humans
- Authors
- Shushan SargsianZe ChenSoo Ching LeeAmicha Robertson14 more author(s)...
- Description
Helminth colonization has been associated with altered composition of the gut microbiota, such as increases in Clostridia. However, it is unclear if specific bacterial species display differential effects on helminth reproduction. This study isolated and sequenced the genome of 13 Clostridia from the Orang Asli, an indigenous population in Malaysia with a high prevalence of helminth infections. Metagenomic...
- Subject
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Genomics
- Access Rights
- Free to All
