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New York City Health and Nutrition Examination Study
- Alternate Title(s)
- NYC HANES
- Authors
- Lorna E. Thorpe
- Description
The NYC Health and Nutritional Examination Survey (NYC HANES), modeled on the National Health and Nutrition Examination Survey (NHANES), is a population-based, cross-sectional study with data collected from physical examinations, clinical and laboratory tests, as well as face-to-face interviews and audio computer-assisted self-interviews (ACASI). It was first conducted in 2004 by the NYC Department...
- Subject
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Chronic DiseaseHealth StatusMental HealthPopulation CharacteristicsRisk Factors
- Access Rights
- Free to All
- Local Expert
- Bonnie KerkerRania Kanchi
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NYU Dataset
MicroRNA-33 Silencing Reprograms the Immune Cell Landscape in Atherosclerotic Plaques
- Authors
- Milessa Silva AfonsoMonika SharmaMartin SchlegelCoen van Solingen11 more author(s)...
- Description
MicroRNA-33 (miR-33) targeted inhibition increases plasma HDL cholesterol and promotes atherosclerosis regression by enhancing reverse cholesterol transport and dampening plaque inflammation. This study showed how miR-33 inhibition alters the dynamic balance and transcriptional landscape of immune cells in atherosclerotic plaques. They used single cell RNA sequencing of aortic CD45+ cells, combined...
- Subject
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Genomics
- Access Rights
- Free to All
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NYU Dataset
DIAPH1 Mediates Progression of Atherosclerosis and Regulates Hepatic Lipid Metabolism in Mice
- Authors
- Laura SenatusLander Egana-GorronoRaquel Lopez-DiezSonia Bergaya17 more author(s)...
- Description
Previous study indicated that the receptor for advanced glycation end products (RAGE) in the progression and regression of atherosclerosis. Therefore, this study examined if Diaphanous 1 (DIAPH1) binds to the RAGE cytoplasmic domain and contributes to progression of atherosclerosis. They intercrossed atherosclerosis prone Ldlr−/− mice with mice devoid of Diaph1 and fed them Western diet for 16 weeks....
- Subject
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Genomics
- Access Rights
- Free to All