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NYU Dataset
Dopamine Neurons in Caenorhabditis elegans Governs Food Response Behaviors
- Authors
- Alice FokBenjamin BrissetteTim HallacyHassan Ahamed3 more author(s)...
- Description
Caenorhabditis elegans (C. elegans) uses specialized mechanosensory neurons to detect food. These neurons release dopamine to suppress foraging and promote dwelling. This study identified genes highly expressed in dopaminergic food-sensing neurons and screened for defects in the food-triggered slowing behavior mediated by these neurons. They found a K2P-family potassium channel gene TWK-2 that mutates...
- Subject
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GenomicsNeuroscience
- Access Rights
- Free to All
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NYU Dataset
Dietary Thiols Accelerates Aging of Caenorhabditis elegans
- Authors
- Ivan GusarovIlya ShamovskyBibhusita PaniLaurent Gautier5 more author(s)...
- Description
Glutathione (GSH) and its precursor, N-acetylcysteine (NAC), are common thiol antioxidants, which are among the most popular dietary supplements. However, the long-term effects of GSH or NAC on healthy animals have not been properly studied. This study examined the effects of prolonged supplementation and chronic restriction of GSH and NAC on Caenorhabditis elegans physiology and lifespan. For RNA...
- Subject
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Genomics
- Access Rights
- Free to All
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NYU Dataset
RNA Sequencing Analysis of Caenorhabditis elegans DAF-18 During Primordial Germ Cell Quiescence
- Authors
- Amanda L. FryAmy K. WebsterJulia BurnettRojin Chitrakar2 more author(s)...
- Description
PTEN is one of the most frequently lost tumor suppressors in human cancers and regulates quiescence of stem cells and cancer cells. The Caenorhabditis elegans daf-18 gene encodes the worm version of PTEN. Previous studies showed that in worms that have lost daf-18 function, primordial germ cells (PGCs) inappropriately begin dividing in the L1 larvae hatched into starvation conditions. This study examined...
- Subject
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Genomics
- Access Rights
- Free to All
