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NYU Dataset
Protein Modifications Discovered Using Differential Tandem Mass Spectrometry Proteomics
- Authors
- Paolo CifaniZhi LiDanmeng LuoMark Grivainis3 more author(s)...
- Description
This dataset was collected to present a spectral alignment method for the identification of protein modifications using high-resolution mass spectrometry proteomics. For this study, they used SAMPEI for spectral alignment-based modified peptide identification. SAMPEI is an open-source algorithm that is designed for the discovery of functional protein and peptide signaling modifications. Human OCI-AML2...
- Subject
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GenomicsProteomics
- Access Rights
- Free to All
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NYU Dataset
Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition
- Authors
- Bryan NgoEugenie KimVictoria Osorio-VasquezSophia Doll36 more author(s)...
- Description
Brain metastasis is the most common intracranial malignancy in adults, which is often fatal. Studies have shown that brain metastases depend on cooperative cellular interactions between tumor cells and specialized cells within the central nervous system (CNS). Metabolic constraints imposed by the serine and glycine limited brain environment restrict metastatic tumor growth. This study showed that 3-phosphoglycerate...
- Subject
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NeuroscienceProteomics
- Access Rights
- Application RequiredAuthor Approval Required
