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NYU Dataset
Behavioral data, fiber photometry recordings, in vitro recordings, and RNA-seq data from posterior amygdala in mice
- Authors
- Takashi YamaguchiDongyu WeiSoomin C. SongByungkook Lim2 more author(s)...
- Description
This dataset contains the following: video recordings of animal behaviors, RNA-seq analysis, in vitro recordings, and fiber photometry recordings for a study on the regulation by the posterior amygdala (PA) of sexual and aggressive behaviors in male mice. The video recordings are of all animal behaviors from two synchronized cameras on the side and top of the cage with frame by frame behavioral annotation...
- Subject
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Neuroscience
- Access Rights
- Free to All
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NYU Dataset
Hierarchical Representations of Aggression in a Hypothalamic-Midbrain Circuit
- Authors
- Annegret L. FalknerDongyu WeiAnjeli SongLi W. Watsek4 more author(s)...
- Description
Ventrolateral area is known as a critical locus for the generation of conspecific aggression, where neurons responding during multiple phases of a social interaction. However, how these neurons organize aggressive action is still unknown. This study found that a hypothalamic-midbrain circuit that represents hierarchically organized signals during aggression. For this study, C57BL/6N, Swiss Webster,...
- Subject
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Neuroscience
- Access Rights
- Application RequiredAuthor Approval Required
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NYU Dataset
Identifying Behavioral Links to Neural Dynamics of Multifiber Photometry Recordings
- Authors
- Yibo ChenJonathan ChienBing DaiDayu Lin1 more author(s)...
- Description
The hypothalamic-midbrain neural circuits play an important role in social interactions involving aggression, defense, and mating. However, how population-averaged neural activity measured by multi-fiber photometry (MFP) for calcium fluorescence signals correlates with social behaviors is a fundamental question. This study proposed a state-space analysis framework to characterize mouse MFP data based...
- Subject
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Neuroscience
- Access Rights
- Free to All
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NYU Dataset
A Dedicated Hypothalamic Oxytocin Circuit Controls Aversive Social Learning
- Authors
- Takuya OsakadaRongzhen YanYiwen JiangDongyu Wei9 more author(s)...
- Description
Fighting is a major means to compete for limited resources in the wild. After the fight ends, the loser continuously avoids close interaction with the winner and readily flees when confronted. The neural mechanisms that underlie the rapid and long-lasting behavioral changes induced by defeat remains unclear. This study identified oxytocin neurons in the retrochiasmatic supraoptic nucleus and oxytocin-receptor-expressing...
- Subject
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Neuroscience
- Access Rights
- Free to All
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NYU Dataset
Hypothalamic Pathway Suppresses Aggression Toward Superior Opponents
- Authors
- Dongyu WeiTakuya OsakadaZhichao GuoTakashi Yamaguchi4 more author(s)...
- Description
Aggression is an innate social behavior and aggression directed toward a stronger opponent in animals can lead to severe physical damage or even death. Therefore, disadvantageous fights to survive and reproduce need to be avoided. This study identified the projection from estrogen receptor alpha-expressing cells in the caudal part of the medial preoptic area (cMPOAEsr1) to the ventrolateral part of...
- Subject
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Neuroscience
- Access Rights
- Free to All
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NYU Dataset
VMHvllCckar Cells Dynamically Control Female Sexual Behaviors
- Authors
- Luping YinKoichi HashikawaYoshiko HashikawaTakuya Osakada3 more author(s)...
- Description
The ventrolateral part of ventromedial hypothalamus (VMHvl) is an important locus for controlling female sexual behaviors. This study identified the cholecystokinin A receptor (Cckar) expressing cells in the lateral VMHvl (VMHvllCckar) as key controllers for female sexual behaviors. They generated a CckarCre knock-in mouse line to target Cckar expressing cells. In addition, they introduced a highly...
- Subject
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Neuroscience
- Access Rights
- Application RequiredAuthor Approval Required