VMHvllCckar Cells Dynamically Control Female Sexual Behaviors
- Description
The ventrolateral part of ventromedial hypothalamus (VMHvl) is an important locus for controlling female sexual behaviors. This study identified the cholecystokinin A receptor (Cckar) expressing cells in the lateral VMHvl (VMHvllCckar) as key controllers for female sexual behaviors. They generated a CckarCre knock-in mouse line to target Cckar expressing cells. In addition, they introduced a highly sexually experienced male mouse into the home cage of singly housed female mice at different reproductive states to gain a comprehensive understanding of female sexual behaviors across reproductive states. This dataset contains electrophysiology, behavioral, fiber photometry, and immunohistochemistry data. The data indicate that VMHvllCckar cells represent a key neural population dynamically controlling female sexual behaviors.
Access
- Restrictions
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Application RequiredAuthor Approval Required
- Instructions
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- Grant Support
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Leon Levy Fellowship in Neuroscience/Leon Levy FoundationMathers Foundation/Mathers FoundationUehara Memorial Foundation/Uehara Memorial FoundationJSPS Overseas Research Fellowship/Japan Society for the Promotion of ScienceOsamu Hayaishi Memorial Scholarship/Japanese Biochemical Society