NYU Dataset
Dopamine Responses and Functions in Nucleus Accumbens Core During Social Behaviors
Part of: Lin Lab |
Part of: Oxytocin U19 BRAIN Initiative |
UID: 10686
- Description
Social behaviors are among the most notable motivated behaviors that are driven by rewarding goals. However, how dopamine (DA), a reward signal, releases during social behaviors has been unclear. This study used a genetically encoded DA sensor, GRABDA2m, to record DA activity in the nucleus accumbens (NAc) core during various social behaviors in male and female mice. They performed optical recording of DA signal by virally expressing Cre-dependent GRABDA2m bilaterally in the NAc core of Drd1-Cre mice. This dataset includes fiber photometry, behavioral, and immunohistochemistry data. These results provide complex information encoded by NAc DA activity during social behaviors and their multistage functional roles.
C57BL/6N mice
BALB/c mice
Swiss Webster mice
Ai9 mice
Drd1-cre mice
Associated Publications
Data Type
Equipment Used
Software Used
Access
- Restrictions
-
Application RequiredAuthor Approval Required
- Instructions
- Please complete the Data Request Form to request access to this dataset. The information included in the form will be sent to the Corresponding Author who will evaluate your request for their data. The Corresponding Author may ask you to provide additional information if necessary.
- Grant Support
-
Mathers Foundation/Mathers FoundationUehara Memorial Foundation/Uehara Memorial FoundationJSPS Overseas Research Fellowship/Japan Society for the Promotion of ScienceOsamu Hayaishi Memorial Scholarship/Japanese Biochemical SocietyVulnerable Brain Project/NYU Langone Health31871087/National Natural Science Foundation of China31925017/National Natural Science Foundation of China
Do you have or know of a dataset that should be added to the catalog? Let us know!