NYU Dataset
Probing Subthreshold Dynamics of Hippocampal Neurons by Pulsed Optogenetics
Part of: Buzsaki Lab |
Part of: Oxytocin U19 BRAIN Initiative |
UID: 10679
- Description
This study investigated the subthreshold dynamics using optogenetic depolarizing pulses in hippocampal neuronal assemblies in freely moving mice to understand how excitatory and inhibitory inputs are integrated by neurons. For the study, they recorded and examined large numbers of CA1 pyramidal neurons simultaneously in freely moving CamKIIα-Cre::Ai32 mice. This dataset contains electrophysiology and imaging data. These results indicate that indirect probing of subthreshold dynamics in neuronal populations permits the disclosing of preexisting assemblies and modes of neuronal operations.
Ai32 mice
CamKIIα-Cre::Ai32 mice
Associated Publications
Data Type
Equipment Used
Software Used
Access
- Restrictions
-
Free to All
- Instructions
- All data needed to evaluate the conclusions in the paper are publicly available in the Buzsaki Lab Webshare and custom MATLAB scripts can be downloaded from GitHub.
Zeiss Confocal Microscope
- Grant Support
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1707316/NSFLeon Levy Fellowship in Neuroscience/Leon Levy Foundation1545858/NSFLT0000717/2018/Human Frontiers Science ProgramEMBO ALTF 1161-2017/European Molecular Biology Organization
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