NYU Dataset
Fluoride Exposure Alters Calcium Signaling and Mitochondrial Function in Enamel Cells
Part of: Lacruz Lab |
UID: 10636
- Description
Fluoride is a naturally occurring mineral that helps build strong teeth and prevent cavities. However, excessive fluoride intake causes dental fluorosis, which are enamel defects that can increase the risk of tooth decay. This study examined the effects of fluoride exposure in enamel cells to assess its impact on calcium signaling. For their investigation, they isolated primary EO cells from Sprague Dawley rats. They also used LS8 cells and HEK293 cells because primary EO cells are difficult to maintain in culture. The dataset includes RNA sequencing data. These data provide a potential mechanism underlying dental fluorosis.
HEK293 cells
LS8 cells
Associated Publications
Data Type
Equipment Used
Software Used
Access
- Restrictions
-
Free to All
- Instructions
- RNA sequencing data have been deposited in NCBI's Gene Expression Omnibus (GEO) database. All other data needed to evaluate the conclusions in the paper are available on PubMed Central (PMC) under Supplementary Materials.
- Grant Support
Do you have or know of a dataset that should be added to the catalog? Let us know!