NYU Dataset
Lateral Entorhinal Cortex Inputs Modulate Hippocampal Dendritic Excitability
Part of: Basu Lab |
UID: 10608
- Description
Lateral entorhinal cortex (LEC) performs important functions for episodic memory processing and coding for contextually salient elements of an environment or experience. This study combined functional circuit mapping and computational modeling to examine the cellular and circuit mechanisms by which long-range glutamatergic LEC projections influence the local activity in the hippocampus. This dataset contains electrophysiology, immunohistochemistry, and modeling data. The data indicates a cortically driven GABAergic microcircuit mechanism that gates nonlinear dendritic computations, which supports compartment-specific coding of multisensory contextual features within the hippocampus.
CR-IRES-Cre mice
VIP-IRES-Flp mice
Dlx-Flp mice
Ai65D mice
Ai14 mice
Ai80D mice
CaMKII-Cre mice
VIP-IRES-Cre mice
SST-IRES-Cre mice
Associated Publications
Data Type
Equipment Used
Software Used
Access
- Restrictions
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Application RequiredAuthor Approval Required
- Instructions
- Please complete the Data Request Form to request access to this dataset. The information included in the form will be sent to the Corresponding Author who will evaluate your request for their data. The Corresponding Author may ask you to provide additional information if necessary.
LN Mini Micromanipulator
Thorlabs LED System
Zeiss LSM 520 META
- Grant Support
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Alfred P. Sloan Foundation/Alfred P. Sloan FoundationWhitehall Foundation/Whitehall FoundationMathers Foundation/Mathers FoundationKlingenstein-Simons Foundation/Klingenstein-Simons FoundationMcKnight Foundation/McKnight FoundationAmerican Epilepsy Society/American Epilepsy SocietyBlas Frangione Foundation/Blas Frangione FoundationNYU Whitehead Fellowship/NYU Whitehead FellowshipGA 863254/European CommissionEVF-2019-508/Einstein Foundation BerlinLeon Levy Foundation/Leon Levy Foundation
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