Brain Temperature Affects Frequency of Hippocampal Sharp Wave Ripples
- Description
Brain temperature shows wide variations across brain states, which fluctuates between sleep and active waking. The frequency of hippocampal sharp wave ripples (SPW-Rs) is also different in the sleeping and waking animals. However, why ripple frequencies in the waking and sleeping brain are different is still unknown. This study examined the correlation between brain temperature variations and the frequency of hippocampal ripples. For this study, Long Evans rats were recorded in their home cages and on a set of behavioral mazes, and the behavioral sessions typically lasted 40 minutes. The dataset contains behavioral and electrophysiology data. This study found that various aspects of SPW-Rs in the sleep-wake cycle are affected by hippocampal temperature changes.
Access
- Restrictions
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Free to All
- Instructions
- The dataset is publicly available in the Buzsaki Lab Databank and all custom code used for this study is available on GitHub.
- Grant Support
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Independent Research Fund Denmark/Independent Research Fund DenmarkLundbeckfonden Denmark/Lundbeckfonden Denmark